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Recombinant Human STEAP4 protein (denatured) (ab177658)

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SDS-PAGE - Recombinant Human STEAP4 protein (denatured) (ab177658)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Tags: His-DDDDK tag N-Terminus
    • Suitable for: SDS-PAGE

    製品の詳細

    • 製品名

      Recombinant Human STEAP4 protein (denatured)

    • 精製度

      > 90 % SDS-PAGE.

    • 発現系

      Escherichia coli

    • アクセッション番号

      Q687X5

    • タンパク質長

      Protein fragment

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMEKT CIDALPLTMN SSEKQETVCI FGTGDFGRSL GLKMLQCGYS VVFGSRNPQKTTLLPSGAEV LSYSEAAKKS GIIIIAIHRE HYDFLTELTE VLNGKILVDI SNNLKINQYP ESNAEYLAHL VPGAHVVKAF NTISAWALQS GALDASRQ

      • 予測される分子量

        21 kDa including tags

      • 領域

        1 to 152

      • タグ

        His-DDDDK tag N-Terminus

      • 配列の追加情報

        NP_078912

    特性

    Our Abpromise guarantee covers the use of ab177658 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      SDS-PAGE

    • 製品の状態

      Liquid
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 8.00
      Constituents: 0.32% Tris HCl, 2.4% Urea, 10% Glycerol (glycerin, glycerine)

    関連情報

    • 別名

      • alpha-induced protein 9
      • Metalloreductase STEAP4
      • six transmembrane prostate protein 2
      • Six-transmembrane epithelial antigen of prostate 4
      • SixTransMembrane protein of prostate 2
      • STAMP 2
      • STAMP2
      • STEA4_HUMAN
      • STEAP 4
      • STEAP family member 4
      • STEAP4
      • TIARP
      • TNFAIP 9
      • TNFAIP9
      • Tumor necrosis factor
      • tumor necrosis factor, alpha-induced protein 9
      • tumor necrosis-alpha-induced adipose-related protein
      see all

    • 機能

      Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.

    • 組織特異性

      Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.

    • 配列類似性

      Belongs to the STEAP family.
      Contains 1 ferric oxidoreductase domain.

    • 細胞内局在

      Cell membrane. Golgi apparatus membrane.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human STEAP4 protein (denatured) (ab177658)
      SDS-PAGE - Recombinant Human STEAP4 protein (denatured) (ab177658)

      15% SDS-PAGE analysis of ab177658 (3 µg).

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab177658 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab177658 は論文での使用が確認できていません。

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