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Recombinant Human SRSF10 protein (ab161147)

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SDS-PAGE - Recombinant Human SRSF10 protein (ab161147)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    製品の詳細

    • 製品名

      Recombinant Human SRSF10 protein

    • 発現系

      Wheat germ

    • タンパク質長

      Protein fragment

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        MSRYLRPPNTSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRP RGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKE

      • 領域

        1 to 100

      • タグ

        GST tag N-Terminus

    特性

    Our Abpromise guarantee covers the use of ab161147 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      ELISA

      Western blot

    • 製品の状態

      Liquid

    • 備考

      This product was previously labelled as FUSIP1.

       

    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    関連情報

    • 別名

      • 40 kDa SR repressor protein
      • 40 kDa SR-repressor protein
      • Anti TLS associated protein with SR repeats
      • arginine/serine-rich 13A
      • FUS interacting protein serine arginine rich 1
      • FUS interacting protein serine arginine rich 2
      • FUS interacting serine arginine rich protein 1
      • FUS-interacting serine-arginine-rich protein 1
      • FUSIP1
      • FUSIP2
      • NSSR
      • OTTHUMP00000015774
      • Serine arginine repressor protein 40 kDa
      • Serine/arginine-rich splicing factor 10
      • SFRS13
      • SFRS13A
      • Splicing factor
      • Splicing factor arginine serine rich 13
      • Splicing factor SRp38
      • SRp38
      • SRp40
      • SRrp40
      • SRS10_HUMAN
      • Srsf10
      • TASR
      • TASR1
      • TASR2
      • TLS associated protein TASR1
      • TLS associated protein TASR2
      • TLS associated protein with Ser Arg repeats
      • TLS associated protein with SR repeats
      • TLS associated serine arginine protein
      • TLS associated serine arginine protein 1
      • TLS associated serine arginine protein 2
      • TLS associated SR protein
      • TLS-associated protein with Ser-Arg repeats
      • TLS-associated protein with SR repeats
      • TLS-associated serine-arginine protein
      • TLS-associated SR protein
      see all

    • 機能

      Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator.

    • 組織特異性

      Widely expressed.

    • 配列類似性

      Belongs to the splicing factor SR family.
      Contains 1 RRM (RNA recognition motif) domain.

    • 翻訳後修飾

      Phosphorylated. Fully dephosphorylated in mitosis and partially dephosphorylated on heat shock. Isoform 3 is phosphorylated on Ser-168.

    • 細胞内局在

      Nucleus speckle. Cytoplasm.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human SRSF10 protein (ab161147)
      SDS-PAGE - Recombinant Human SRSF10 protein (ab161147)
      ab161147 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (1)

    ab161147 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab161147 は 1 報の論文で使用されています。

    • Song H  et al. A novel biomarker NIFK-AS1 promotes hepatocellular carcinoma cell cycle progression through interaction with SRSF10. J Gastrointest Oncol 13:1927-1941 (2022). PubMed: 36092356

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