AB134856

Recombinant Human SOX13 protein

Name: Recombinant Human SOX13 protein (ab134856) | Abcam
Brand: Abcam Limited
SKU: AB134856
Price: 100000 JPY
Availability: InStock

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Recombinant Human SOX13 protein is a Human Full Length protein, in the 2 to 622 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.

別名を表示する

Transcription factor SOX-13, Islet cell antigen 12, SRY (Sex determining region Y)-box 13, Type 1 diabetes autoantigen ICA12, SOX13

Key facts

精製度

>90% SDS-PAGE

ab134856 was expressed in E. coli as inclusion bodies, refolded using the unique “temperature shift inclusion body refolding” technology, chromatographically purified and sterile filtered.

発現系

Escherichia coli

アプリケーション

SDS-PAGE

applications

生物活性

アクセッション番号

Q9UN79

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 8 Constituents: 3.4% DL-Arginine, 0.32% Tris HCl, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.02% EDTA

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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配列情報

[{"linker":null,"sequence":"29aa_Tag_ SMRSPIS AQLALDGVGT MVNCTIKSEE KKEPCHEAPQ GSATAAEPQP GDPARASQDS ADPQAPAQGN FRGSWDCSSP EGNGSPEPKR PGVSEAASGS QEKLDFNRNL KEVVPAIEKL LSSDWKERFL GRNSMEAKDV KGTQESLAEK ELQLLVMIHQ LSTLRDQLLT AHSEQKNMAA MLFEKQQQQM ELARQQQEQI AKQQQQLIQQ QHKINLLQQQ IQQVNMPYVM IPAFPPSHQP LPVTPDSQLA LPIQPIPCKP VEYPLQLLHS PPAPVVKRPG AMATHHPLQE PSQPLNLTAK PKAPELPNTS SSPSLKMSSC VPRPPSHGGP TRDLQSSPPS LPLGFLGEGD AVTKAIQDAR QLLHSHSGAL DGSPNTPFRK DLISLDSSPA KERLEDGCVH PLEEAMLSCD MDGSRHFPES RNSSHIKRPM NAFMVWAKDE RRKILQAFPD MHNSSISKIL GSRWKSMTNQ EKQPYYEEQA RLSRQHLEKY PDYKYKPRPK RTCIVEGKRL RVGEYKALMR TRRQDARQSY VIPPQAGQVQ MSSSDVLYPR AAGMPLAQPL VEHYVPRSLD PNMPVIVNTC SLREEGEGTD DRHSVADGEM YRYSEDEDSE GEEKSDGELV VLTDLEESGG GGSPGRRRRR RRRRRR","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":622,"aminoAcidStart":2,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9UN79","tags":[]}]

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出荷温度及び保存条件

製品の状態

Liquid

出荷温度

Blue Ice

短期保存温度

-20°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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一般的な情報

機能

Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3' (PubMed : 10871192). Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the developing spinal tube (By similarity). Binds to the gene promoter of MBP and acts as a transcriptional repressor (By similarity). Binds to and modifies the activity of TCF7/TCF1, thereby inhibiting transcription and modulates normal gamma-delta T-cell development and differentiation of IL17A expressing gamma-delta T-cells (By similarity). Regulates expression of BLK in the differentiation of IL17A expressing gamma-delta T-cells (By similarity). Promotes brown adipocyte differentiation (By similarity). Inhibitor of WNT signaling (PubMed : 20028982).

細胞内局在性

Nucleus

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information Transcription factor SOX-13

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Recombinant Human SOX13 protein