Recombinant Human Smoothened protein (ab114221)
Key features and details
- Expression system: Wheat germ
- Suitable for: ELISA, SDS-PAGE, WB
製品の詳細
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製品名
Recombinant Human Smoothened protein
Smoothened タンパク質・ペプチド 製品一覧 -
発現系
Wheat germ -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
NLWLVEAEISPELQKRLGRKKKRRKRKKEVCPLAPPPELHPPAPAPSTIP RLPQLPRQKCLVAAGAWGAGDSCRQ GAWTLVSNPFCPEPSPPQDPFLP SAPAPVAWAHGRRQGLGPIHSRTNLMDTELMDADSDF -
予測される分子量
40 kDa including tags -
領域
653 to 787
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特性
Our Abpromise guarantee covers the use of ab114221 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
ELISA
SDS-PAGE
Western blot
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.3% Glutathione, 0.79% Tris HCl
関連情報
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別名
- Frizzled family member 11
- FZD11
- Gx
see all -
機能
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia. -
配列類似性
Belongs to the G-protein coupled receptor Fz/Smo family.
Contains 1 FZ (frizzled) domain. -
細胞内局在
Membrane. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human Smoothened protein (ab114221)ab114221 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab114221 は論文での使用が確認できていません。
