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Recombinant Human SLC40A1 protein (ab153316)

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SDS-PAGE - Recombinant Human SLC40A1 protein (ab153316)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    製品の詳細

    • 製品名

      Recombinant Human SLC40A1 protein

    • 発現系

      Wheat germ

    • タンパク質長

      Full length protein

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFL VELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQN VSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTAT AITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGS PVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLN LHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWV SYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASA ITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDL SVSPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSANIVPETSPESV PIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMN YLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKL FACGPDAKEVRKENQANTSVV

      • 領域

        1 to 571

      • タグ

        GST tag N-Terminus

    特性

    Our Abpromise guarantee covers the use of ab153316 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      ELISA

      Western blot

    • 製品の状態

      Liquid
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    関連情報

    • 別名

      • Ferroportin
      • Ferroportin 1
      • Ferroportin-1
      • FPN1
      • HFE4
      • IREG1
      • iron regulated gene 1
      • Iron regulated transporter 1
      • Iron-regulated transporter 1
      • MST079
      • MSTP079
      • MTP1
      • putative ferroportin 1 variant IIIA
      • putative ferroportin 1 variant IIIB
      • S40A1_HUMAN
      • SLC11A3
      • SLC11A3, formerly
      • SLC40A1
      • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3
      • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3, formerly
      • solute carrier family 40 (iron-regulated transporter), member 1
      • Solute carrier family 40 member 1
      see all

    • 機能

      May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).

    • 組織特異性

      Expressed in placenta, intestine, muscle and spleen.

    • 関連疾患

      Defects in SLC40A1 are the cause of hemochromatosis type 4 (HFE4) [MIM:606069]. HFE4 is an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin before elevation of the transferrin saturation.

    • 配列類似性

      Belongs to the SLC40A transporter family.

    • 細胞内局在

      Cell membrane. Localized to the basolateral membrane of polarized epithelial cells.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human SLC40A1 protein (ab153316)
      SDS-PAGE - Recombinant Human SLC40A1 protein (ab153316)
      ab153316 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab153316 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab153316 は論文での使用が確認できていません。

    レビューと Q&A

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