Hello. We're improving abcam.com and we'd welcome your feedback.

Hello. We're improving abcam.com and we'd welcome your feedback.

Infomation icon

We haven't added this to the BETA yet

New BETA website

New BETA website

Hello. We're improving abcam.com and we'd welcome your feedback.

Take a look at our BETA site and see what we’ve done so far.

Switch on our new BETA site

Now available

Search and browse selected products

  • A selection of primary antibodies

Purchase these through your usual distributor

In the coming months

  • Additional product types
  • Supporting content
  • Sign in to your account
  • Purchase online

Recombinant Human Sin3b protein (ab161600)

Submit a review Submit a question
SDS-PAGE - Recombinant Human Sin3b protein (ab161600)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, WB

    製品の詳細

    • 製品名

      Recombinant Human Sin3b protein

    • 発現系

      Wheat germ

    • アクセッション番号

      O75182

    • タンパク質長

      Full length protein

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQ VKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF NAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQVPYKEDK PQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNT RGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCE MHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVG KYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSP FLG

      • 領域

        1 to 353

      • タグ

        GST tag N-Terminus

    特性

    Our Abpromise guarantee covers the use of ab161600 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      ELISA

      Western blot

    • 製品の状態

      Liquid

    • 備考

       

       

    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    関連情報

    • 別名

      • Histone deacetylase complex subunit Sin3b
      • Paired amphipathic helix protein Sin3b
      • SIN3 homolog B transcription regulator
      • SIN3 transcription regulator family member B
      • SIN3 transcription regulator homolog B
      • SIN3B
      • SIN3B_HUMAN
      • Transcriptional corepressor Sin3b
      see all

    • 機能

      Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.

    • 配列類似性

      Contains 3 PAH (paired amphipathic helix) domains.

    • 翻訳後修飾

      Ubiquitinated by RNF220 that leads to proteasomal degradation.

    • 細胞内局在

      Nucleus.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human Sin3b protein (ab161600)
      SDS-PAGE - Recombinant Human Sin3b protein (ab161600)
      ab161600 on a 12.5% SDS-PAGE stained with Coomassie Blue.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab161600 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab161600 は論文での使用が確認できていません。

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    There are currently no Customer reviews or Questions for ab161600.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com