Recombinant human SHP1 protein (ab61135)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% Densitometry
- Active: Yes
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, Functional Studies
製品の詳細
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製品名
Recombinant human SHP1 protein
SHP1 タンパク質・ペプチド 製品一覧 -
精製度
> 90 % Densitometry. -
発現系
Escherichia coli -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
タグ
GST tag N-Terminus
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関連製品
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Affibody® Molecule
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Related Products
特性
Our Abpromise guarantee covers the use of ab61135 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Functional Studies
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.418% MOPS, 0.00174% PMSF, 0.00385% DTT, 30% Glycerol (glycerin, glycerine), 50% Sodium chlorideThis product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- 70Z-SHP
- EC 3.1.3.48
- HCP
see all -
機能
Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. -
組織特異性
Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells. -
配列類似性
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
Contains 2 SH2 domains.
Contains 1 tyrosine-protein phosphatase domain. -
翻訳後修飾
Phosphorylated on serine and tyrosine residues. -
細胞内局在
Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II. - Information by UniProt
画像
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Functional Studies - Recombinant human SHP1 protein (ab61135)The specific activity of SHP1 (ab61135) was determined to be 1100 nmol phosphate released/min/mg as per activity assay protocol
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SDS-PAGE - Recombinant human SHP1 protein (ab61135)SDS PAGE analysis of ab61135 -
SDS-PAGE - Recombinant human SHP1 protein (ab61135)SDS PAGE analysis of ab61135 -
Functional Studies - Recombinant human SHP1 protein (ab61135)Sample Kinase Activity Plot. -
SDS-PAGE - Recombinant human SHP1 protein (ab61135)ab61135 on SDS-PAGE, MW ~93 kDa.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab61135 は論文での使用が確認できていません。