AB276605

Recombinant Human SEZ6L2 protein (His tag)

Name: Recombinant Human SEZ6L2 protein (His tag) (ab276605) | Abcam
Brand: Abcam Limited
SKU: AB276605
Price: 63000 JPY
Availability: InStock

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Recombinant Human SEZ6L2 protein (His tag) is a Human Fragment protein, in the 1 to 736 aa range, expressed in HEK 293 cells, with >95%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

別名を表示する

PSK, UNQ1903/PRO4349, SEZ6L2, Seizure 6-like protein 2

1 Images

SDS-PAGE - Recombinant Human SEZ6L2 protein (His tag) (AB276605)

SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human SEZ6L2 protein (His tag) (AB276605)

SDS-PAGE analysis of ab276605.

Key facts

精製度

>95% SDS-PAGE

エンドトキシンレベル

< 1 EU/µg

発現系

HEK 293 cells

アプリケーション

SDS-PAGE

applications

生物活性

アクセッション番号

Q6UXD5

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 7.4 Constituents: PBS

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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配列情報

[{"sequence":"MGTPRAQHPPPPQLLFLILLSCPWIQGLPLKEEEILPEPGSETPTVASEALAELLHGALLRRGPEMGYLPGSDRDPTLATPPAGQTLAVPSLPRATEPGTGPLTTAVTPNGVRGAGPTAPELLTPPPGTTAPPPPSPASPGPPLGPEGGEEETTTTIITTTTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPS","proteinLength":"Fragment","predictedMolecularWeight":"77.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":736,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6UXD5","tags":[{"tag":"His","terminus":"C-Terminus"}]}]

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出荷温度及び保存条件

出荷温度

Ambient - Can Ship with Ice

短期保存温度

-20°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

SEZ6L2 also known as Seizure 6-like protein 2 is a transmembrane protein with an approximate mass of 100 kDa. This protein contains several domains including CUB and Sushi/SCR/CCP domains which suggest roles in cell signal recognition and interaction. SEZ6L2 expresses mainly in the brain with a concentration in regions such as the cerebral cortex and hippocampus implicating it within processes critical to neurological development and function.

Biological function summary

SEZ6L2 has important roles in synaptic transmission and plasticity. It is part of a larger complex that influences the development and maintenance of synapses. Current research suggests that SEZ6L2 affects the signaling pathways in neurons and may involve the modulation of synaptic strength impacting cognitive functions such as learning and memory.

Pathways

SEZ6L2 is involved in the regulation of synaptic signaling pathways. It interacts significantly with proteins in the cAMP signaling pathway which is important for translating extracellular signals into cellular responses and neurotrophic pathway which involves proteins like BDNF. These pathways are essential for cellular survival differentiation and plasticity in neural cells further linking SEZ6L2 to neurological processes.

SEZ6L2 has associations with several neurological conditions including epilepsy and autism spectrum disorders. In epilepsy SEZ6L2 interacts with other seizure-related proteins that affect neuronal excitability and network stability. For autism spectrum disorders changes in SEZ6L2 expression or function likely alter synaptic connectivity and signal transmission influencing behavioral and cognitive symptoms associated with this disorder.

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製品の性状

製品の状態

Lyophilized

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一般的な情報

機能

May contribute to specialized endoplasmic reticulum functions in neurons.

配列の類似性

Belongs to the SEZ6 family.

翻訳後修飾

O-glycosylated with core 1 or possibly core 8 glycans.

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

May contribute to specialized endoplasmic reticulum functions in neurons.

See full target information SEZ6L2

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Abcam product promise

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Recombinant Human SEZ6L2 protein (His tag)