Recombinant Human RTN3/HAP protein (ab153066)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
製品の詳細
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製品名
Recombinant Human RTN3/HAP protein -
発現系
Wheat germ -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHD LIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIY KSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLII RLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEK YKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE -
領域
1 to 236 -
タグ
GST tag N-Terminus
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特性
Our Abpromise guarantee covers the use of ab153066 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Western blot
ELISA
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製品の状態
Liquid -
備考
This product was previously labelled as RTN3.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
関連情報
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別名
- ASYIP
- Neuroendocrine specific protein like 2
- Neuroendocrine-specific protein-like 2
see all -
機能
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. -
組織特異性
Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma. -
配列類似性
Contains 1 reticulon domain. -
細胞内局在
Endoplasmic reticulum membrane. Golgi apparatus membrane. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human RTN3/HAP protein (ab153066)ab153066 on a 12.5% SDS-PAGE stained with Coomassie Blue.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab153066 は論文での使用が確認できていません。
