Recombinant Human RPLP0 protein
Recombinant Human RPLP0 protein
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Recombinant Human RPLP0 protein is a Human Full Length protein, in the 2 to 317 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.
別名を表示する
Large ribosomal subunit protein uL10, 60S acidic ribosomal protein P0, 60S ribosomal protein L10E, RPLP0
Reactivity data
配列情報
出荷温度及び保存条件
出荷温度
短期保存期間
短期保存温度
長期保存温度
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
RPLP0 participates actively in ribosome structure and function. It forms part of the ribosomal stalk together with the P1 and P2 proteins facilitating interactions with GTPase translation factors during protein synthesis. This ribosomal complex is important for elongation phase of protein translation where it actively assists in the accurate and efficient elongation of polypeptide chains. By participating in the ribosome's structural framework RPLP0 drives the translation process influencing protein output in cells. This makes it essential for overall protein homeostasis.
Pathways
RPLP0 is deeply embedded within the processes of translation and ribosome biogenesis. It associates with the major pathway of ribosome assembly wherein new ribosomes are synthesized and configured. It functions alongside other ribosomal proteins like RPLP1 and RPLP2 which work together to maintain efficient protein synthesis. The interaction among these proteins within the translation pathway highlights the integrated nature of RPLP0 in facilitating cellular protein production.
製品の性状
製品の状態
Liquid
補足情報
ab205214 was expressed in E.coli as inclusion bodies, refolded using a unique “temperature shift inclusion body refolding” technology, chromatographically purified and sterile-filtered.
一般的な情報
機能
Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
配列の類似性
Belongs to the universal ribosomal protein uL10 family.
翻訳後修飾
Ubiquitinated at Lys-264 by RNF14 and RNF25 in response to ribosome collisions (ribosome stalling).
細胞内局在性
Nucleus
ターゲットの情報
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