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AB176043

Recombinant Human RPL31 protein (His tag N-Terminus)

Recombinant Human RPL31 protein (His tag N-Terminus)

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Recombinant Human RPL31 protein (His tag N-Terminus) is a Human Full Length protein, in the 1 to 125 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

別名を表示する

Large ribosomal subunit protein eL31, 60S ribosomal protein L31, RPL31

1 Images
SDS-PAGE - Recombinant Human RPL31 protein (His tag N-Terminus) (AB176043)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human RPL31 protein (His tag N-Terminus) (AB176043)

15% SDS-PAGE analysis of ab176043 (3μg).

Key facts

精製度

>85% SDS-PAGE

発現系

Escherichia coli

タグ

His tag N-Terminus

アプリケーション

Mass Spec, SDS-PAGE

applications

生物活性

No

アクセッション番号

P62899

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 8 Constituents: 50% Glycerol (glycerin, glycerine), 1.17% Sodium chloride, 0.32% Tris-HCl buffer, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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配列情報

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN","proteinLength":"Full Length","predictedMolecularWeight":"16.9 kDa","actualMolecularWeight":null,"aminoAcidEnd":125,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P62899","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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出荷温度及び保存条件

出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
False
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

RPL31 also known as Ribosomal Protein L31 is a component of the 60S subunit of the ribosome. This protein weighs approximately 14 kDa. It plays an important role in protein synthesis within the cell. RPL31 is widely expressed in many tissues including the liver kidney and lung. Its presence in these tissues indicates its importance in cellular function and metabolism.
Biological function summary

This ribosomal protein facilitates the assembly and stability of ribosomal structures enabling proper translation and protein synthesis. RPL31 is part of the larger ribosomal complex which includes multiple RNA molecules and many ribosomal proteins. It assists in maintaining the integrity of the ribosome during translation which is fundamental for efficient protein synthesis.

Pathways

RPL31 plays a role in the translation pathway and the ribosome biogenesis pathway. It interacts with other ribosomal proteins such as RPL17 and RPL26. These pathways are critical for cell growth and proliferation. RPL31's function within these pathways highlights its role in assembling ribosomal units and ensuring correct translation and protein production within cells.

RPL31 has been linked to Diamond-Blackfan anemia a rare blood disorder. This connection stems from its role in ribosomal structure and function. Mutations affecting RPL31 or related ribosomal proteins like RPS19 can disrupt normal ribosome biogenesis leading to disorders linked to defective erythropoiesis. Such findings emphasize the importance of RPL31 in maintaining normal cellular and hematopoietic function.
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製品の性状

製品の状態

Liquid

補足情報

Purified using conventional chromatography techniques

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一般的な情報

機能

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 32669547).

配列の類似性

Belongs to the eukaryotic ribosomal protein eL31 family.

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製品プロトコール

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ターゲットの情報

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 32669547).
See full target information 60S ribosomal protein L31
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Primary Antibodies

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