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AB167904

Recombinant Human RPL26 protein

Recombinant Human RPL26 protein

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Recombinant Human RPL26 protein is a Human Full Length protein, in the 1 to 145 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

別名を表示する

Large ribosomal subunit protein uL24, 60S ribosomal protein L26, RPL26

1 Images
SDS-PAGE - Recombinant Human RPL26 protein (AB167904)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human RPL26 protein (AB167904)

15% SDS-PAGE analysis of ab167904 (3µg).

Key facts

精製度

>85% SDS-PAGE

発現系

Escherichia coli

タグ

His tag N-Terminus

アプリケーション

Mass Spec, SDS-PAGE

applications

生物活性

No

アクセッション番号

P61254

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 8 Constituents: 40% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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製品の詳細

This product was previously labelled as Ribosomal protein L26
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配列情報

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMKFNPFVTSDRSKNRKRHFNAPSHIRRKIMSSPLSKELRQKYNVRSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPSKVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEETIEKMQE","proteinLength":"Full Length","predictedMolecularWeight":"19.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":145,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P61254","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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出荷温度及び保存条件

出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
False
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

RPL26 also known as Ribosomal Protein L26 is a component of the 60S subunit of the ribosome. It has a mass of approximately 17 kDa. This protein primarily expresses in tissues with high levels of protein synthesis including muscle liver and brain. As part of the ribosome RPL26 plays an essential role in the synthesis of proteins by facilitating the assembly of amino acids into polypeptide chains.
Biological function summary

RPL26 contributes to the complex process of translation by ensuring the stability and proper function of the ribosome. As a structural part of the large ribosomal subunit it helps maintain the integrity of the ribosomal architecture necessary for effective translation. This protein also indirectly affects mRNA processing and mRNA stability both of which influence the efficiency of protein synthesis.

Pathways

RPL26 participates in translation and ribosome biogenesis pathways. It interacts closely with other ribosomal proteins and rRNA to form the functional ribosome. Within these pathways RPL26 is linked with proteins like RPL5 and RPL11 which also contribute to the assembly and stability of the ribosome. Efficient protein synthesis by this pathway is fundamental for cellular growth and proliferation.

RPL26 is associated with conditions like Diamond-Blackfan anemia and cancer. Diamond-Blackfan anemia is a ribosomopathy resulting from mutations in ribosomal proteins including RPL26 disrupting normal erythropoiesis. The depletion or malfunction of RPL26 can also influence cancer progression by altering the translational capacity of cancer cells affecting proteins like p53 that control cell cycle and apoptosis.
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製品の性状

製品の状態

Liquid

補足情報

ab167904 is purified using conventional chromatography techniques.

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一般的な情報

機能

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 26100019, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 26100019, PubMed : 32669547).

配列の類似性

Belongs to the universal ribosomal protein uL24 family.

翻訳後修飾

Ufmylated by UFL1 in response to endoplasmic reticulum stress, promoting reticulophagy of endoplasmic reticulum sheets.

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製品プロトコール

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ターゲットの情報

Component of the large ribosomal subunit (PubMed : 23636399, PubMed : 26100019, PubMed : 32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed : 23636399, PubMed : 26100019, PubMed : 32669547).
See full target information RPL26
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組合せ製品

Primary Antibodies

AB157111

Anti-RPL26 antibody

Western blot - Anti-RPL26 antibody (AB157111)

  • 0
  • 0
Primary Antibodies

AB59567

Anti-RPL26 + RPL26L1 antibody

Western blot - Anti-RPL26 + RPL26L1 antibody (AB59567)

  • 3
  • 3
Primary Antibodies

AB109305

Anti-UFM1 antibody [EPR4264(2)]

KO Validated|RabMAb|Recombinant

Western blot - Anti-UFM1 antibody [EPR4264(2)] (AB109305)

  • 5
  • 4
Proteins & Peptides

AB269005

Recombinant Human Tau (mutated L266V) protein

SDS-PAGE - Recombinant Human Tau (mutated L266V) protein (AB269005)

  • 0
  • 0

Abcam product promise

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