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AB70614

Recombinant human ROR2 protein

Recombinant human ROR2 protein

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Recombinant human ROR2 protein is a Human Fragment protein, in the 427 to 943 aa range, expressed in Baculovirus infected Sf9 cells, with >80%, suitable for SDS-PAGE, FuncS.

別名を表示する

NTRKR2, ROR2, Tyrosine-protein kinase transmembrane receptor ROR2

4 Images
Functional Studies - Recombinant human ROR2 protein (AB70614)
  • FuncS

Unknown

Functional Studies - Recombinant human ROR2 protein (AB70614)

Kinase assay

Functional Studies - Recombinant human ROR2 protein (AB70614)
  • FuncS

Unknown

Functional Studies - Recombinant human ROR2 protein (AB70614)

The specific activity of ROR2 (ab70614) was determined to be 0.2 nmol/min/mg as per activity assay protocol

SDS-PAGE - Recombinant human ROR2 protein (AB70614)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human ROR2 protein (AB70614)

SDS-PAGE showing ab70614 at approximately 86kDa.

SDS-PAGE - Recombinant human ROR2 protein (AB70614)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human ROR2 protein (AB70614)

SDS PAGE analysis of ab70614

Key facts

精製度

>80% Densitometry

発現系

Baculovirus infected Sf9 cells

タグ

GST tag N-Terminus

アプリケーション

FuncS, SDS-PAGE

applications

生物活性

Yes

生物学的活性

Active

アクセッション番号

Q01974

アニマルフリー

No

キャリアフリー

No

Human

バッファー組成

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.79% Tris HCl, 0.00385% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.0038% EGTA, 0.00292% EDTA, 0.00174% PMSF

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>Kinase assay.</p>" } } }

製品の詳細

ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

配列情報

[{"linker":null,"sequence":"","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":943,"aminoAcidStart":427,"nature":"Recombinant","expressionSystem":null,"accessionNumber":"Q01974","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

出荷温度及び保存条件

出荷温度
Dry Ice
短期保存温度
-80°C
長期保存温度
-80°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
True

製品の性状

製品の状態

Liquid

補足情報

Purity is lot specific. Please contact our technical Support team for details.Affinity purified.

一般的な情報

機能

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed : 17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443).

配列の類似性

Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.

製品プロトコール

ターゲットの情報

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed : 17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed : 25029443).
See full target information ROR2

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