Recombinant Human RAD18 protein (ab112417)
Key features and details
- Expression system: Wheat germ
- Suitable for: SDS-PAGE, WB, ELISA
製品の詳細
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製品名
Recombinant Human RAD18 protein -
生理活性
useful for Antibody Production and Protein Array -
発現系
Wheat germ -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
予測される分子量
83 kDa including tags -
領域
1 to 495
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab112417 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Western blot
ELISA
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製品の状態
Liquid -
備考
This product is useful for Antibody Production and Protein Array.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
(Glutathione is reduced)
関連情報
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別名
- 2810024C04Rik
- DNA repair protein rad18
- E3 ubiquitin-protein ligase RAD18
see all -
機能
E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. -
パスウェイ
Protein modification; protein ubiquitination. -
配列類似性
Belongs to the RAD18 family.
Contains 1 RING-type zinc finger.
Contains 1 SAP domain.
Contains 1 UBZ-type zinc finger. -
細胞内局在
Nucleus. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human RAD18 protein (ab112417)12.5% SDS-PAGE Stained with Coomassie Blue.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab112417 は 1 報の論文で使用されています。
- Yu R et al. LncRNA CTBP1-DT-encoded microprotein DDUP sustains DNA damage response signalling to trigger dual DNA repair mechanisms. Nucleic Acids Res 50:8060-8079 (2022). PubMed: 35849344
