Recombinant Human PXR protein (ab82082)
Key features and details
- Expression system: Baculovirus infected insect cells
- Purity: > 90% Affinity purified
- Suitable for: GSA
製品の詳細
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製品名
Recombinant Human PXR protein
PXR タンパク質・ペプチド 製品一覧 -
生理活性
1 unit equals 1 nanogram of purified protein. ab82082 binds to DNA as a heterodimer with RXR alpha; 1000U (1ug) required. -
精製度
> 90 % Affinity purified.
ab82082 is purified by an affinity column in combination with FPLC chromatography and is greater than 90% homogeneous. ab82082 contains no detectable proteases, DNase and RNase activity. -
発現系
Baculovirus infected insect cells -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human
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特性
Our Abpromise guarantee covers the use of ab82082 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Gel Supershift Assays
EMSA
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製品の状態
Liquid -
備考
1 unit equals 1 nanogram of purified protein. ab82082 binds to DNA as a heterodimer with RXR alpha; 1000U (1ug) required. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.9
Constituents: 0.75% Potassium chloride, 0.0154% DTT, 0.316% Tris HCl, 0.00584% EDTA, 20% Glycerol (glycerin, glycerine)
関連情報
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別名
- BXR
- Nr1i2
- NR1I2_HUMAN
see all -
機能
Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes. -
組織特異性
Expressed in liver, colon and small intestine. -
配列類似性
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab82082 は論文での使用が確認できていません。