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AB225984

Recombinant Human Putative 40S ribosomal protein-like (His tag)

Recombinant Human Putative 40S ribosomal protein-like (His tag)

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Recombinant Human Putative 40S ribosomal protein-like (His tag) is a Human Full Length protein, in the 1 to 176 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE.

別名を表示する

RPS10L, RPS10P5, Putative ribosomal protein eS10-like, Putative 40S ribosomal protein S10-like

1 Images
SDS-PAGE - Recombinant Human Putative 40S ribosomal protein-like (His tag) (AB225984)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human Putative 40S ribosomal protein-like (His tag) (AB225984)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) analysis of ab225984 with 5% enrichment gel and 15% separation gel.

Key facts

精製度

>90% SDS-PAGE

発現系

Escherichia coli

タグ

6x His tag N-Terminus SUMO tag N-Terminus

アプリケーション

SDS-PAGE

applications

生物活性

No

アクセッション番号

Q9NQ39

アニマルフリー

No

キャリアフリー

No

Human

バッファー組成

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

配列情報

[{"linker":null,"sequence":"MLMPKKNRIAIHELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQSLKSRGCVKEQFAWRHFYWYLTNEGSQYLRDYLHLPPEIVPATLHLPPEIVPATLHRSRPETGRPRPKGLEGKRPARLTRREADRDTYRRCSVPPGADKKAEAGAGSATEFQFRGRCGRGRGQPPQ","proteinLength":"Full Length","predictedMolecularWeight":"36.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":176,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9NQ39","tags":[{"tag":"6x His","terminus":"N-Terminus"},{"tag":"SUMO","terminus":"N-Terminus"}]}]

出荷温度及び保存条件

製品の状態
Liquid
出荷温度
Blue Ice
短期保存温度
-20°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
False

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The Putative 40S ribosomal protein-like sometimes referred to as RPL40-like functions as a structural component within the ribosomal subunit involved in translation. Its molecular weight is approximately 40 kDa. This protein localizes extensively in the cytoplasm specifically integrating into the small ribosomal subunit. Expression occurs widely across various tissues indicating a general role in protein synthesis.
Biological function summary

The Putative 40S ribosomal protein-like participates in the formation of the ribosome complex which is important for the translation of mRNA into proteins. As part of the ribosomal machinery this protein plays a role in ensuring the accuracy of translation and the efficient production of polypeptides. The interaction within the ribosome highlights its involvement in maintaining cellular protein homeostasis which is important for cell growth and function.

Pathways

The Putative 40S ribosomal protein-like integrates into the protein synthesis process contributing to the mTOR signaling pathway. The mTOR pathway regulates cell growth proliferation and survival and the protein's role links to its coordination in translation regulation. It also interacts with various translational factors such as eIF3 and eIF4 promoting efficient ribosomal initiation and elongation during protein synthesis.

Research links abnormal expression of ribosomal proteins including the Putative 40S ribosomal protein-like to certain cancers and hereditary ribosomopathies. Alterations in its expression or function may influence tumorigenesis due to disrupted protein synthesis and cell cycle control. Additionally RPL40-like can interact with other ribosomal proteins like RPL5 and RPL11 which are associated with Diamond-Blackfan anemia a disorder resulting from defective ribosome function.

一般的な情報

配列の類似性

Belongs to the eukaryotic ribosomal protein eS10 family.

製品プロトコール

ターゲットの情報

See full target information RPS10P5

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