Recombinant Human PRUNE protein (ab153466)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
製品の詳細
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製品名
Recombinant Human PRUNE protein -
発現系
Wheat germ -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MEDYLQGCRAALQESRPLHVVLGNEACDLDSTVSALALAFYLAKTTEAEE VFVPVLNIKRSELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQL TLILVDHHILSKSDTALEEAVAEVLDHRPIEPKHCPPCHVSVELVGSCAT LVTERILQGAPEILDRQTAALLHGTIILDCVNMDLKIGKATPKDSKYVEK LEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQGVKVAI SAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLA IFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKK LLPLLQEALSAYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQ DEEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASL SKK -
領域
1 to 453 -
タグ
GST tag N-Terminus
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特性
Our Abpromise guarantee covers the use of ab153466 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Western blot
ELISA
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
関連情報
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別名
- DRES-17
- DRES17
- Drosophila-related expressed sequence 17
see all -
機能
Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1. -
組織特異性
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas. -
配列類似性
Belongs to the PPase class C family. Prune subfamily. -
細胞内局在
Cytoplasm. Nucleus. Cell junction > focal adhesion. In some transfected cells a nuclear staining is also observed. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human PRUNE protein (ab153466)ab153466 on a 12.5% SDS-PAGE stained with Coomassie Blue.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab153466 は 1 報の論文で使用されています。
- Scoma ER et al. Human Prune Regulates the Metabolism of Mammalian Inorganic Polyphosphate and Bioenergetics. Int J Mol Sci 24:N/A (2023). PubMed: 37762163
