Recombinant Human PEN2 protein (ab289755)
Key features and details
- Expression system: Cell free
- Purity: >= 85% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human PEN2 protein
PEN2 タンパク質・ペプチド 製品一覧 -
精製度
>= 85 % SDS-PAGE. -
発現系
Cell free -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
Yes -
由来
Recombinant -
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生物種
Human -
配列
MNLERVSNEE KLNLCRKYYL GGFAFLPFLW LVNIFWFFRE AFLVPAYTEQ SQIKGYVWRS AVGFLFWVIV LTSWITIFQI YRPRWGALGD YLSFTIPLGT P -
予測される分子量
15 kDa including tags -
領域
1 to 101 -
タグ
His tag N-Terminus -
配列の追加情報
10xHis
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特性
Our Abpromise guarantee covers the use of ab289755 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 0.24% Tris, 0.87% Sodium chloride, 0.05% dodecyl 2-(trimethylazaniumyl)ethyl phosphate, 6% Trehalose
関連情報
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別名
- Gamma secretase subunit PEN 2
- Gamma Secretase Subunit PEN2
- Gamma-secretase subunit PEN-2
see all -
機能
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity. -
組織特異性
Widely expressed. Expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain. -
配列類似性
Belongs to the PEN-2 family. -
細胞内局在
Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Predominantly located in the endoplasmic reticulum and in the cis-Golgi. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human PEN2 protein (ab289755)SDS-PAGE analysis of ab289755
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab289755 は論文での使用が確認できていません。
