Recombinant human PDGF AA protein (ab9702)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
製品の詳細
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製品名
Recombinant human PDGF AA protein
PDGF AA タンパク質・ペプチド 製品一覧 -
精製度
> 98 % SDS-PAGE.
Sterile filtered Greater than 98% pure by HPLC analyses. Endotoxin level is less than 0.1 ng per g (1EU/g). -
発現系
Escherichia coli -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
予測される分子量
24 kDa
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特性
Our Abpromise guarantee covers the use of ab9702 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Functional Studies
SDS-PAGE
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製品の状態
Lyophilized -
備考
The biological activity is determined by the dose-dependent stimulation of the proliferation of BALB/c 3T3 cells, is < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituent: 0.06% Acetic acid
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成For lot specific reconstitution information please contact our Scientific Support Team.
関連情報
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別名
- PDGF A
- PDGF A chain
- PDGF subunit A
see all -
機能
Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. -
配列類似性
Belongs to the PDGF/VEGF growth factor family. -
ドメイン
The long form contains a basic insert which acts as a cell retention signal. -
細胞内局在
Secreted. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab9702 は 3 報の論文で使用されています。
- Wang A et al. miR-29a-5p/STAT3 Positive Feedback Loop Regulates TETs in Colitis-Associated Colorectal Cancer. Inflamm Bowel Dis 26:524-533 (2020). PubMed: 31750910
- Katz DB et al. An immortalized human adipose-derived stem cell line with highly enhanced chondrogenic properties. Biochem Biophys Res Commun 530:252-258 (2020). PubMed: 32828295
- Gomez JA et al. Ventral tegmental area astrocytes orchestrate avoidance and approach behavior. Nat Commun 10:1455 (2019). PubMed: 30926783