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Recombinant Human PAIP2 protein (ab89367)

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SDS-PAGE - Recombinant Human PAIP2 protein (ab89367)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Suitable for: SDS-PAGE

    製品の詳細

    • 製品名

      Recombinant Human PAIP2 protein

    • 精製度

      > 90 % SDS-PAGE.
      ab89367 is purified using conventional chromatography techniques.

    • 発現系

      Escherichia coli

    • タンパク質長

      Full length protein

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

    特性

    Our Abpromise guarantee covers the use of ab89367 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      SDS-PAGE

    • 製品の状態

      Liquid
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine)

    関連情報

    • 別名

      • PABP-interacting protein 2
      • PAIP-2
      • PAIP2
      • PAIP2_HUMAN
      • poly(A) binding protein interacting protein 2
      • Poly(A)-binding protein-interacting protein 2
      • Polyadenylate-binding protein-interacting protein 2
      see all

    • 機能

      Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.

    • 配列類似性

      Belongs to the PAIP2 family.

    • ドメイン

      Only the PABPC1-interacting motif-1 (PAM1) interferes with the binding of PABPC1 to poly(A) RNA and translation initiation.

    • 細胞内局在

      Cytoplasm.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human PAIP2 protein (ab89367)
      SDS-PAGE - Recombinant Human PAIP2 protein (ab89367)

      SDS-PAGE analysis of Recombinant Human PAIP2 protein (ab89367), under reducing conditions. Proteins visualized by coomassie blue stain.

      Lane 1: Molecular Weight Standards

      Lane 2: 3 µg Recombinant Human PAIP2 protein

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab89367 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab89367 は論文での使用が確認できていません。

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