Recombinant Human NUP214 protein (ab152837)
Key features and details
- Expression system: Wheat germ
- Suitable for: ELISA, WB, SDS-PAGE
製品の詳細
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製品名
Recombinant Human NUP214 protein -
発現系
Wheat germ -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MGDEMDAMIPEREMKDFQFRALKKVRIFDSPEELPKERSSLLAVSNKYGL VFAGGASGLQIFPTKNLLIQNKPGDDPNKIVDKVQGLLVPMKFPIHH -
予測される分子量
36 kDa including tags -
領域
1 to 97
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特性
Our Abpromise guarantee covers the use of ab152837 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
ELISA
Western blot
SDS-PAGE
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
関連情報
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別名
- 214 kDa nucleoporin
- CAIN
- CAN
see all -
機能
May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex. -
組織特異性
Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development. -
関連疾患
Note=A chromosomal aberration involving NUP214 is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with DEK. It results in the formation of a DEK-CAN fusion gene.
Note=A chromosomal aberration involving NUP214 is found in some cases of acute undifferentiated leukemia (AUL). Translocation t(6;9)(q21;q34.1) with SET. -
ドメイン
Contains FG repeats. -
翻訳後修飾
Probably glycosylated as it reacts with wheat germ agglutinin (WGA). -
細胞内局在
Nucleus > nuclear pore complex. Cytoplasmic filaments. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human NUP214 protein (ab152837)12.5% SDS-PAGE analysis of ab152837 stained with Coomassie Blue.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab152837 は論文での使用が確認できていません。
