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Recombinant Human NDUFS2 protein (ab152560)

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SDS-PAGE - Recombinant Human NDUFS2 protein (ab152560)

    Key features and details

    • Expression system: Wheat germ
    • Tags: GST tag N-Terminus
    • Suitable for: ELISA, SDS-PAGE, WB

    製品の詳細

    • 製品名

      Recombinant Human NDUFS2 protein
      NDUFS2 タンパク質・ペプチド 製品一覧

    • 発現系

      Wheat germ

    • アクセッション番号

      O75306

    • タンパク質長

      Full length protein

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        MAALRALCGFRGVAAQVLRPGAGVRLPIQPSRGVRQWQPDVEWAQQFGGA VMYPSKETAHWKPPPWNDVDPPKDTIVKNITLNFGPQHPAAHGVLRLVME LSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMMCNEQA YSLAVEKLLNIRPPPRAQWIRVLFGEITRLLNHIMAVTTHALDLGAMTPF FWLFEEREKMFEFYERVSGARMHAAYIRPGGVHQDLPLGLMDDIYQFSKN FSLRLDELEELLTNNRIWRNRTIDIGVVTAEEALNYGFSGVMLRGSGIQW DLRKTQPYDVYDQVEFDVPVGSRGDCYDRYLCRVEEMRQSLRIIAQCLNK MPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAI EAPKGEFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAI IGTQDIVFGEVDR

      • 予測される分子量

        79 kDa including tags

      • 領域

        1 to 463

      • タグ

        GST tag N-Terminus

    特性

    Our Abpromise guarantee covers the use of ab152560 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      ELISA

      SDS-PAGE

      Western blot

    • 製品の状態

      Liquid
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    関連情報

    • 別名

      • CI 49
      • CI 49kD
      • CI-49kD
      • Complex 1, mitochondrial respiratory chain, 49 KD subunit
      • Complex I 49kD
      • Complex I 49kDa subunit
      • Complex I-49kD
      • mitochondrial
      • NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa
      • NADH dehydrogenase (ubiquinone) Fe S protein 2, 49kDa (NADH coenzyme Q reductase)
      • NADH dehydrogenase [ubiquinone] iron sulfur protein 2, mitochondrial
      • NADH dehydrogenase [ubiquinone] iron-sulfur protein 2
      • NADH ubiquinone oxidoreductase 49 kDa subunit
      • NADH ubiquinone oxidoreductase NDUFS2 subunit
      • NADH-ubiquinone oxidoreductase 49 kDa subunit
      • NADH:ubiquinone oxidoreductase core subunit S2
      • Ndufs2
      • NDUS2_HUMAN
      see all

    • 機能

      Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

    • 関連疾患

      Defects in NDUFS2 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.

    • 配列類似性

      Belongs to the complex I 49 kDa subunit family.

    • 細胞内局在

      Mitochondrion inner membrane.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human NDUFS2 protein (ab152560)
      SDS-PAGE - Recombinant Human NDUFS2 protein (ab152560)
      12.5% SDS-PAGE analysis of ab152560 stained with Coomassie Blue.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab152560 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab152560 は論文での使用が確認できていません。

    レビューと Q&A

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