Recombinant Human MK2 protein (ab45154)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% Densitometry
- Tags: GST tag N-Terminus
製品の詳細
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製品名
Recombinant Human MK2 protein
MK2 タンパク質・ペプチド 製品一覧 -
精製度
> 90 % Densitometry.
Purified via GST Tag -
発現系
Escherichia coli -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
領域
46 to 400 -
タグ
GST tag N-Terminus
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特性
Our Abpromise guarantee covers the use of ab45154 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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製品の状態
Liquid -
備考
This product was previously labelled as MAPKAP Kinase 2
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.0418% EGTA, 0.00174% PMSF, 0.385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
関連情報
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別名
- MAP kinase activated protein Kinase 2
- MAP kinase-activated protein kinase 2
- MAPK activated protein kinase 2
see all -
機能
Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity. -
組織特異性
Expressed in all tissues examined. -
配列類似性
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 1 protein kinase domain. -
翻訳後修飾
Phosphorylated and activated by MAP kinase. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab45154 は論文での使用が確認できていません。