Recombinant Human MGP protein (denatured) (ab113156)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human MGP protein (denatured)
MGP タンパク質・ペプチド 製品一覧 -
精製度
> 90 % SDS-PAGE.
ab113156 was purified using conventional chromatography techniques. -
発現系
Escherichia coli -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MGSSHHHHHHSSGLVPRGSHMYESHESMESYELNPFINRRNANTFISPQQ RWRAKVQERIRERSKPVHELNREACDDYRLCERYAMVYGYNAAYNRYF -
予測される分子量
12 kDa including tags -
領域
20 to 96 -
タグ
His tag N-Terminus
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-
製品の詳細
Recombinant Human MGP protein
関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab113156 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine)
関連情報
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別名
- Cell growth inhibiting gene 36 protein
- Cell growth-inhibiting gene 36 protein
- GAMMA-CARBOXYGLUTAMIC ACID PROTEIN, MATRIX
see all -
機能
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation. -
関連疾患
Defects in MGP are the cause of Keutel syndrome (KS) [MIM:245150]. KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia. -
配列類似性
Belongs to the osteocalcin/matrix Gla protein family.
Contains 1 Gla (gamma-carboxy-glutamate) domain. -
翻訳後修飾
Requires vitamin K-dependent gamma-carboxylation for its function. -
細胞内局在
Secreted. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human MGP protein (denatured) (ab113156)15% SDS-PAGE showing ab113156 (3 µg) at approximately 11.8 kDa.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab113156 は 1 報の論文で使用されています。
- Liu Q et al. Chondrocyte-derived exosomes promote cartilage calcification in temporomandibular joint osteoarthritis. Arthritis Res Ther 24:44 (2022). PubMed: 35164837