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AB190407

Recombinant human MAK protein

Recombinant human MAK protein

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Recombinant human MAK protein is a Human Full Length protein, in the 1 to 623 aa range, expressed in Baculovirus infected Sf9 cells, with >75%, suitable for WB, FuncS.

別名を表示する

Serine/threonine-protein kinase MAK, Male germ cell-associated kinase, MAK

4 Images
Functional Studies - Recombinant human MAK protein (AB190407)
  • FuncS

Unknown

Functional Studies - Recombinant human MAK protein (AB190407)

The specific activity of MAK (ab190407) was determined to be 35 nmol/min/mg as per activity assay protocol

Functional Studies - Recombinant human MAK protein (AB190407)
  • FuncS

Supplier Data

Functional Studies - Recombinant human MAK protein (AB190407)

The specific activity of ab190407 was determined to be 40 nmol/min/mg.

SDS-PAGE - Recombinant human MAK protein (AB190407)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant human MAK protein (AB190407)

The putity of ab190407 was determined to be >75% by densitometry.

SDS-PAGE - Recombinant human MAK protein (AB190407)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant human MAK protein (AB190407)

SDS PAGE analysis of ab190407

Key facts

精製度

>75% SDS-PAGE

発現系

Baculovirus infected Sf9 cells

タグ

GST tag N-Terminus

アプリケーション

WB, FuncS

applications

生物活性

Yes

生物学的活性

The specific activity of ab190407 was determined to be 40 nmol/min/mg.

アクセッション番号

P20794

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 7.5 Constituents: 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.79% Tris HCl, 0.31% Glutathione, 0.004% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.003% EDTA, 0.002% PMSF

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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製品の詳細

ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity
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配列情報

[{"sequence":"MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQVVGQPQPKTSQQPLQPIQPPQNLSVQQPPKQQSQEKPPQTLFPSIVKNMPTKPNGTLSHKSGRRRWGQTIFKSGDSWEELEDYDFGASHSKKPSMGVFKEKRKKDSPFRLPEPVPSGSNHSTGENKSLPAVTSLKSDSELSTAPTSKQYYLKQSRYLPGVNPKKVSLIASGKEINPHTWSNQLFPKSLGPVGAELAFKRSNAGNLGSYATYNQSGYIPSFLKKEVQSAGQRIHLAPLNATASEYTWNTKTGRGQFSGRTYNPTAKNLNIVNRAQPIPSVHGRTDWVAKYGGHR","proteinLength":"Full Length","predictedMolecularWeight":"78 kDa","actualMolecularWeight":null,"aminoAcidEnd":623,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Baculovirus infected Sf9 cells","accessionNumber":"P20794","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]
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出荷温度及び保存条件

出荷温度
Dry Ice
短期保存温度
-80°C
長期保存温度
-80°C
保管に関する情報
Avoid freeze / thaw cycle
True
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製品の性状

製品の状態

Liquid

補足情報

Assessed by densitometry. Affinity purified.

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一般的な情報

機能

Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells.

配列の類似性

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

翻訳後修飾

Autophosphorylated. Phosphorylated on serine and threonine residues.

細胞内局在性

Nucleus

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製品プロトコール

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ターゲットの情報

Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells.
See full target information MAK
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組合せ製品

Primary Antibodies

AB279383

Anti-MAK antibody [OTI1G2]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAK antibody [OTI1G2] (AB279383)

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