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AB235805

Recombinant Human MAGEA10 protein (His tag)

Recombinant Human MAGEA10 protein (His tag)

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Recombinant Human MAGEA10 protein (His tag) is a Human Full Length protein, in the 1 to 369 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE.

別名を表示する

MAGE10, MAGEA10, Melanoma-associated antigen 10, Cancer/testis antigen 1.10, MAGE-10 antigen, CT1.10

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SDS-PAGE - Recombinant Human MAGEA10 protein (His tag) (AB235805)
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Supplier Data

SDS-PAGE - Recombinant Human MAGEA10 protein (His tag) (AB235805)

ab235805 analyzed by (Tris-Glycine gel) discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Key facts

精製度

>85% SDS-PAGE

発現系

Escherichia coli

タグ

10x His tag N-Terminus

アプリケーション

SDS-PAGE

applications

生物活性

No

アクセッション番号

P43363

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 7.2 - 7.4 Constituents: Tris buffer, 50% Glycerol (glycerin, glycerine)

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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配列情報

[{"sequence":"MPRAPKRQRCMPEEDLQSQSETQGLEGAQAPLAVEEDASSSTSTSSSFPSSFPSSSSSSSSSCYPLIPSTPEEVSADDETPNPPQSAQIACSSPSVVASLPLDQSDEGSSSQKEESPSTLQVLPDSESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAEILESVIRNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQSMPKTGILILILSIVFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGEPRKLLTQDWVQENYLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEEERAQDRIATTDDTTAMASASSSATGSFSYPE","proteinLength":"Full Length","predictedMolecularWeight":"46.3 kDa","actualMolecularWeight":null,"aminoAcidEnd":369,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P43363","tags":[{"tag":"10x His","terminus":"N-Terminus"}]}]
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出荷温度及び保存条件

出荷温度
Blue Ice
短期保存温度
-20°C
長期保存温度
-20°C
保管に関する情報
Avoid freeze / thaw cycle
False
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

MAGEA10 also known as Melanoma Antigen Family A 10 is a member of the MAGE (Melanoma Antigen Gene) family. This protein has a molecular mass of about 36 kDa. MAGEA10 is expressed in various tumor cells and some male germline cells in the testis but not in normal somatic tissues. The expression pattern makes it an interesting target for cancer research and potential therapeutic interventions.
Biological function summary

The function of MAGEA10 remains not fully understood but it likely plays a role in cell proliferation and survival. It is not a component of any known protein complex. Research suggests that MAGEA10 might modulate cellular processes by interacting with other proteins impacting pathways related to oncogenesis and cell cycle regulation.

Pathways

MAGEA10 appears to be involved in critical pathways associated with cancer progression and possibly immune evasion. It interacts with proteins involved in cell signaling pathways such as the p53 pathway which is pivotal in regulating the cell cycle and apoptosis. MAGEA10 may influence these pathways by affecting gene transcription and modulating protein-protein interactions.

MAGEA10 has a strong connection to cancer particularly in melanoma and lung cancer. Overexpression of MAGEA10 in these cancers suggests a possible role in tumor growth and metastasis. The protein is part of cancer-testis antigens similar to MAGEA1 another member of the same family implicated in various malignancies suggesting that targeting MAGEA10 could aid in developing specific cancer immunotherapies.
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製品の性状

製品の状態

Liquid

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一般的な情報

機能

Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.

細胞内局在性

Nucleus

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製品プロトコール

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ターゲットの情報

Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
See full target information MAGEA10
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