Recombinant human Macrophage Inflammatory Protein 1 alpha / CCL3 (ab9674)
Key features and details
- Expression system: Escherichia coli
- Purity: > 99% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
製品の詳細
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製品名
Recombinant human Macrophage Inflammatory Protein 1 alpha / CCL3
MIP-1 alpha/CCL3 タンパク質・ペプチド 製品一覧 -
精製度
> 99 % SDS-PAGE.
Sterile filtered Greater than 99% by HPLC analyses. Endotoxin level is less than 0.1 ng per g (1EU/g). -
発現系
Escherichia coli -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
予測される分子量
10 kDa
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製品の詳細
Recombinant human MIP-1 alpha/CCL3 protein
関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab9674 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Functional Studies
SDS-PAGE
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製品の状態
Lyophilized -
備考
The biological activity of this product is determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Please reconstitute this product in 200ul water.
関連情報
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別名
- C C motif chemokine 3
- CCL 3
- CCL3
see all -
機能
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). -
配列類似性
Belongs to the intercrine beta (chemokine CC) family. -
翻訳後修飾
N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. -
細胞内局在
Secreted. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab9674 は 1 報の論文で使用されています。
- Jeong JH & Kang EB Effects of treadmill exercise on PI3K/AKT/GSK-3ß pathway and tau protein in high-fat diet-fed rats. J Exerc Nutrition Biochem 22:9-14 (2018). PubMed: 29673239