AB639

Recombinant human LTA protein

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Recombinant human LTA protein is a Human Full Length protein, expressed in Escherichia coli, with >98%, suitable for SDS-PAGE, FuncS.

別名を表示する

TNFB, TNFSF1, LTA, Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1

Key facts

精製度

>98% SDS-PAGE

発現系

Escherichia coli

アプリケーション

SDS-PAGE, FuncS

applications

生物活性

Yes

生物学的活性

The ED50, determined by the cytolysis of murine L929 cells in the presence of actinomycin D, is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 10⁷ units/mg.

アクセッション番号

P01374

アニマルフリー

キャリアフリー

種

Human

再構成

Reconstitute with 20µl pure water.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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製品の詳細

The ED50, determined by the cytolysis of murine L929 cells in the presence of actinomycin D, is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 10⁷ units/mg. This product was previously labelled as TNF beta

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配列情報

[{"sequence":"MLPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL","proteinLength":"Full Length","predictedMolecularWeight":"18.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":0,"aminoAcidStart":0,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P01374","tags":[]}]

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出荷温度及び保存条件

出荷温度

Blue Ice

短期保存期間

Up to 6 months

短期保存温度

+4°C

長期保存温度

-20°C

True

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製品の性状

製品の状態

Lyophilized

補足情報

Sterile filtered Greater than 98% pure by HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).

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一般的な情報

機能

Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed : 9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR (PubMed : 24248355). Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.

配列の類似性

Belongs to the tumor necrosis factor family.

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information LTA

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Abcam product promise

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Recombinant human LTA protein