Recombinant Human KLHL12 protein (ab169886)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Tags: T7 tag N-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human KLHL12 protein -
精製度
> 90 % SDS-PAGE.
The final product was refolded using a unique “temperature shift inclusion body refolding” technology and chromatographically purified. -
発現系
Escherichia coli -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MASMTGGQQMGRGEFMGGIMAPKDIMTNTHAKSILNSMNSLRKSNTLCDV TLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKGKPYVDIQGLTASTME ILLDFVYTETVHVTVENVQELLPAACLLQLKGVKQACCEFLESQLDPSNC LGIRDFAETHNCVDLMQAAEVFSQKHFPEVVQHEEFILLSQGEVEKLIKC DEIQVDSEEPVFEAVINWVKHAKKEREESLPNLLQYVRMPLLTPRYITDV IDAEPFIRCSLQCRDLVDEAKKFHLRPELRSQMQGPRTRARLGANEVLLV VGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLHDRIYVIG GYDGRSRLSSVECLDYTADEDGVWYSVAPMNVRRGLAGATTLGDMIYVSG GFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLGGYD GLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFDGTA HLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNSLLS SIECYDPIIDSWEVVTSMGTQRCDAGVCVLREK -
予測される分子量
63 kDa -
領域
1 to 568 -
タグ
T7 tag N-Terminus
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab169886 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituent: 0.32% Tris HCl
Contains NaCl, KCl, EDTA, arginine, DTT and Glycerol.
関連情報
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別名
- C3IP1
- CUL3 interacting protein 1
- CUL3-interacting protein 1
see all -
機能
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. -
組織特異性
Highly expressed in testis and at lower levels in the submandibular salivary gland. -
配列類似性
Contains 1 BTB (POZ) domain.
Contains 6 Kelch repeats. -
ドメイン
The BTB domain is required for interaction with CUL3. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab169886 は論文での使用が確認できていません。
