Recombinant Human ING2 protein (ab127136)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 75% Densitometry
- Suitable for: SDS-PAGE, WB
製品の詳細
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製品名
Recombinant Human ING2 protein
ING2 タンパク質・ペプチド 製品一覧 -
精製度
> 75 % Densitometry.
Purity was determined to be >75% by densitometry. Affinity purified. -
発現系
Baculovirus infected Sf9 cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
予測される分子量
62 kDa including tags -
領域
1 to 280
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特性
Our Abpromise guarantee covers the use of ab127136 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
Western blot
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.005% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol (glycerin, glycerine), 0.29% Sodium chloride
関連情報
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別名
- ING 1 like tumor suppressor protein
- ING 1L
- ING 2
see all -
機能
Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs). -
組織特異性
Widely expressed. Higher expressed in colon-cancer tumor than in normal colon tissues. -
配列類似性
Belongs to the ING family.
Contains 1 PHD-type zinc finger. -
ドメイン
The PHD-type zinc finger domain binds to phosphoinositides (PtdInsPs), including phosphatidylinositol 5-phosphate (PtdIns(5)P). -
細胞内局在
Nucleus. Predominantly nuclear. Localized to chromatin and nuclear matrix. Upon reduced PtdIns(5)P levels seems to be released from chromatin and, at least partially, translocated to the cytoplasm. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human ING2 protein (ab127136)SDS-PAGE analysis of ab127136.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab127136 は論文での使用が確認できていません。