Recombinant Human IL1R1 Protein (Active) (ab290103)
Key features and details
- Expression system: HEK 293 cells
- Purity: >= 95% HPLC
- Endotoxin level: <= 0.005 Eu/µg
- Active: Yes
製品の詳細
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製品名
Recombinant Human IL1R1 Protein (Active)
IL1 Receptor I/IL-1R-1 タンパク質・ペプチド 製品一覧 -
生理活性
Fully biologically active determined by its ability to inhibit IL-1 beta dependent proliferation of D10S cells. The ED50 ≤ 3.8 ug/ml, corresponding to a specific activity of 2.6 x 103 units/mg.
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精製度
>= 95 % HPLC. -
エンドトキシン・レベル
<=0.005 Eu/µg -
発現系
HEK 293 cells -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
Yes -
由来
Recombinant -
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生物種
Human -
配列
DKCKEREEKIILVSSANEIDVRPCPLNPNEHKGTITWYKDDSKTPVSTEQ ASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSSYCLRIKISAKFVENEPNL CYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQWYKDCKPLLLD NIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITLEE NKPTRPVIVSPANETMEVDLGSQIQLICNVTGQLSDIAYWKWNGSVIDED DPVLGEDYYSVENPANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGI DAAYIQLIYPVT -
領域
21 to 338 -
配列の追加情報
N-terminal glycine.
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特性
Our Abpromise guarantee covers the use of ab290103 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at Room Temperature. Store at Room Temperature.
pH: 7.4
Constituents: 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Monobasic dihydrogen potassium phosphate, 10.26% TrehaloseThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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再構成Reconstitute with phosphate buffered saline. Store lyophilized form at room temperature. Reconstitute, aliquot and store at -80°C for 12 months or +4°C for 1week. Avoid repeated freeze-thaw. Lyophilized contents may appear as either a translucent film or a white power. This variance does not affect the quality of the product
関連情報
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別名
- Antigen CD121a
- CD121 antigen-like family member A
- CD121a
see all -
機能
Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2. -
配列類似性
Belongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain. -
細胞内局在
Membrane. - Information by UniProt
画像
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Biological Activity - Recombinant Human IL1R1 Protein (Active) (ab290103)
Fully biologically active determined by its ability to inhibit IL-1 beta dependent proliferation of D10S cells. The ED50 ≤ 3.8 ug/ml, corresponding to a specific activity of 2.6 x 103 units/mg.
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SDS-PAGE - IL1 Receptor I/IL-1R-1 protein (ab290103)SDS-PAGE analysis of ab290103 -
Mass Spectrometry - IL1 Receptor I/IL-1R-1 protein (ab290103)Mass determination by ESI-TOF.
Predicted MW is 35920.91 Da. (+/- 10 Da by ESI-TOF). Observed MW is 35927.89 Da.
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HPLC - IL1 Receptor I/IL-1R-1 protein (ab290103)HPLC analysis of ab290103
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab290103 は論文での使用が確認できていません。
