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AB288525

Recombinant Human IL-34 protein (Active)

Recombinant Human IL-34 protein (Active)

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Recombinant Human IL-34 protein (Active) is a Human Full Length protein, in the 21 to 242 aa range, expressed in HEK 293 cells, with >95%, <0.005 EU/µg endotoxin level, suitable for SDS-PAGE, FuncS, Mass Spec, HPLC, Cell Culture.

別名を表示する

C16orf77, IL34, Interleukin-34, IL-34

4 Images
Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)
  • Mass Spec

Supplier Data

Mass Spectrometry - Recombinant Human IL-34 protein (Active) (AB288525)

ESI TOF analysis of ab288525.

Predicted MW is 25289.0 Da (+/- 10 Da by ESI TOF). Observed MW is25290.13

Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)
  • FuncS

Supplier Data

Functional Studies - Recombinant Human IL-34 protein (Active) (AB288525)

Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.

HPLC - Recombinant Human IL-34 protein (Active) (AB288525)
  • HPLC

Supplier Data

HPLC - Recombinant Human IL-34 protein (Active) (AB288525)

HPLC analysis of ab288525.

SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human IL-34 protein (Active) (AB288525)

SDS-PAGE analysis of ab288525.

Key facts

精製度

>95% SDS-PAGE

Purity by HPLC =95%

エンドトキシンレベル

<0.005 EU/µg

発現系

HEK 293 cells

タグ

Tag free

アプリケーション

FuncS, HPLC, Cell Culture, SDS-PAGE, Mass Spec

applications

生物活性

Yes

生物学的活性

Fully biologically active determined by dose dependent proliferation of PBMCs cells. ED50 is ≤2.082 ng/ml, corresponding to a specific activity of 4.8 x 105 units/mg.

アクセッション番号

Q6ZMJ4

アニマルフリー

Yes

キャリアフリー

No

種

Human

再構成

Reconstitute in PBS

バッファー組成

pH: 7.4 Constituents: 10.26% Trehalose, 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Potassium phosphate monobasic

storage-buffer

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組合せ製品

Reagents, Controls & Accessories

AB313995

Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (15 - 170 kDa) (AB313995)

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AB50036

Recombinant human TGF beta 1 protein (Active)

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AB259396

Recombinant human M-CSF protein (Active)

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Mass Spectrometry - Recombinant human M-CSF protein (Active) (AB259396)

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AB259376

Recombinant human GM-CSF protein (Active)

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Mass Spectrometry - Recombinant human GM-CSF protein (Active) (AB259376)

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Proteins & Peptides

AB290831

Recombinant Human TREM2 protein

SDS-PAGE - Recombinant Human TREM2 protein (AB290831)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Cell Culture": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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配列情報

[{"linker":null,"sequence":"NEPLEMWPLTQNEECTVTGFLRDKLQYRSRLQYMKHYFPINYKISVPYEGVFRIANVTRLQRAQVSERELRYLWVLVSLSATESVQDVLLEGHPSWKYLQEVETLLLNVQQGLTDVEVSPKVESVLSLLNAPGPNLKLVRPKALLDNCFRVMELLYCSCCKQSSVLNWQDCEVPSPQSCSPEPSLQYAATQLYPPPPWSPSSPPHSTGSVRPVRAQGEGLLP","proteinLength":"Full Length","predictedMolecularWeight":"25.29 kDa","actualMolecularWeight":"25.9 kDa","aminoAcidEnd":242,"aminoAcidStart":21,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q6ZMJ4","tags":[]}]
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出荷温度及び保存条件

製品の状態
Lyophilized
出荷温度
Ambient - Can Ship with Ice
短期保存温度
Ambient
長期保存温度
Ambient
True
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一般的な情報

機能

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.

配列の類似性

Belongs to the IL-34 family.

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製品プロトコール

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ターゲットの情報

Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1.
See full target information IL34
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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
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