Recombinant Human ICA 512/PTPRN protein (ab42590)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: GST tag N-Terminus
- Suitable for: Phosphatase Activity
製品の詳細
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製品名
Recombinant Human ICA 512/PTPRN protein -
精製度
> 95 % SDS-PAGE. -
発現系
Escherichia coli -
アクセッション番号
-
タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
予測される分子量
59 kDa including tags -
領域
693 to 979 -
タグ
GST tag N-Terminus
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特性
Our Abpromise guarantee covers the use of ab42590 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Phosphatase Activity
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製品の状態
Liquid -
備考
This protein may be useful for the study of regulation, and to dephosphorylate target substrates. It seems to lack intrinic enzyme activity.
Previously labelled as PTPIA2 / PTPRN.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.307% Glutathione, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.394% Tris HCl, 0.05% Tween, 0.0584% EDTA, 50% Glycerol (glycerin, glycerine), 0.438% Sodium chloride
関連情報
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別名
- CA 512
- FLJ16131
- IA 2
see all -
機能
Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2. -
組織特異性
Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary. -
配列類似性
Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
Contains 1 tyrosine-protein phosphatase domain. -
翻訳後修飾
Appears to undergo multiple proteolytic cleavage at consecutive basic residues. -
細胞内局在
Membrane. Neuroendocrine secretory granules. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab42590 は論文での使用が確認できていません。