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Recombinant Human HIF1AN/FIH-1 protein (ab86916)

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SDS-PAGE - Recombinant Human HIF1AN/FIH-1 protein (ab86916)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Suitable for: SDS-PAGE

    製品の詳細

    • 製品名

      Recombinant Human HIF1AN/FIH-1 protein

    • 精製度

      > 90 % SDS-PAGE.
      ab86916 was purified using conventional chromatography techniques.

    • 発現系

      Escherichia coli

    • タンパク質長

      Full length protein

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        MAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP RAEELIENEE PVVLTDTNLV YPALKWDLEY LQENIGNGDF SVYSASTHKF LYYDEKKMAN FQNFKPRSNR EEMKFHEFVE KLQDIQQRGG EERLYLQQTL NDTVGRKIVM DFLGFNWNWI NKQQGKRGWG QLTSNLLLIG MEGNVTPAHY DEQQNFFAQI KGYKRCILFP PDQFECLYPY PVHHPCDRQS QVDFDNPDYE RFPNFQNVVG YETVVGPGDV LYIPMYWWHH IESLLNGGIT ITVNFWYKGA PTPKRIEYPL KAHQKVAIMR NIEKMLGEAL GNPQEVGPLL NTMIKGRYN

    特性

    Our Abpromise guarantee covers the use of ab86916 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      SDS-PAGE

    • 製品の状態

      Liquid

    • 備考

      Previously labelled as HIF1AN.

    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

      pH: 8.00
      Constituent: 0.316% Tris HCl

    関連情報

    • 別名

      • DKFZp762F1811
      • Factor inhibiting HIF-1
      • Factor inhibiting HIF1
      • FIH 1
      • FIH-1
      • FIH1
      • FLJ20615
      • FLJ22027
      • HIF1AN
      • HIF1N_HUMAN
      • Hypoxia inducible factor 1 alpha inhibitor
      • Hypoxia inducible factor 1 alpha subunit inhibitor
      • Hypoxia inducible factor asparagine hydroxylase
      • Hypoxia-inducible factor 1-alpha inhibitor
      • Hypoxia-inducible factor asparagine hydroxylase
      • Peptide aspartate beta dioxygenase
      see all

    • 機能

      Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.

    • 配列類似性

      Contains 1 JmjC domain.

    • 細胞内局在

      Nucleus.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human HIF1AN/FIH-1 protein (ab86916)
      SDS-PAGE - Recombinant Human HIF1AN/FIH-1 protein (ab86916)
      15% SDS-PAGE analysis of 3µg ab86916

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab86916 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab86916 は論文での使用が確認できていません。

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