Recombinant human Granzyme A protein (ab157288)
Key features and details
- Expression system: Escherichia coli
- Purity: >= 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
製品の詳細
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製品名
Recombinant human Granzyme A protein
Granzyme A タンパク質・ペプチド 製品一覧 -
生理活性
Specific Activity: ~110U/µg protein. One unit is defined as the amount of enzyme that hydrolyzes 1nmol Z-Lys-SBzl per min. at 25°C in 0.05M TRIS, pH 8.0, containing 0.15M NaCl, 0.01% Triton X-100 and 0.3mM DTNB.
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精製度
>= 98 % SDS-PAGE. -
発現系
Escherichia coli -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQV ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINK YVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKV CNDRNHYNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSF GLENKCGDPRGPGVYILLSKKHLNWIIMTIKGAV -
予測される分子量
52 kDa -
領域
29 to 262
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特性
Our Abpromise guarantee covers the use of ab157288 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Functional Studies
SDS-PAGE
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製品の状態
Liquid -
備考
Do not dilute to more than 0.2mg/ml. Do not store dilute solutions (1-1000ng/ml) for more than 24 hours. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.98% MES, 10% Glycerol (glycerin, glycerine), 3.04% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- CTL tryptase
- CTLA3
- Cytolytic t cell and natural killer cell specific trypsin like serine protease
see all -
機能
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Involved in apoptosis. -
配列類似性
Belongs to the peptidase S1 family. Granzyme subfamily.
Contains 1 peptidase S1 domain. -
細胞内局在
Secreted. Cytoplasmic granule. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab157288 は論文での使用が確認できていません。