AB162723

Recombinant Human GPCR GPR85 protein (GST tag N-Terminus)

Name: Recombinant Human GPCR GPR85 protein (ab162723) | Abcam
Brand: Abcam Limited
SKU: AB162723
Price: 118000 JPY
Availability: InStock

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Recombinant Human GPCR GPR85 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 370 aa range, expressed in Wheat germ, suitable for ELISA, WB.

別名を表示する

SREB2, GPR85, Probable G-protein coupled receptor 85, Super conserved receptor expressed in brain 2

1 Images

SDS-PAGE - Recombinant Human GPCR GPR85 protein (GST tag N-Terminus) (AB162723)

SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human GPCR GPR85 protein (GST tag N-Terminus) (AB162723)

ab162723 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

発現系

Wheat germ

アプリケーション

ELISA, WB

applications

生物活性

アクセッション番号

P60893

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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配列情報

[{"sequence":"MANYSHAADNILQNLSPLTAFLKLTSLGFIIGVSVVGNLLISILLVKDKTLHRAPYYFLLDLCCSDILRSAICFPFVFNSVKNGSTWTYGTLTCKVIAFLGVLSCFHTAFMLFCISVTRYLAIAHHRFYTKRLTFWTCLAVICMVWTLSVAMAFPPVLDVGTYSFIREEDQCAFQHRSFRANDSLGFMLLLALILLATQLVYLKLIFFVHDRRKMKPVQFVAAVSQNWTFHGPGASGQAAANWLAGFGRGPTPPTLLGIRQNANTTGRRRLLVLDEFKMEKRISRMFYIMTFLFLTLWGPYLVACYWRVFARGPVVPGGFLTAAVWMSFAQAGINPFVCIFSNRELRRCFSTTLLYCRKSRLPREPYCVI","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":370,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"P60893","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

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出荷温度及び保存条件

出荷温度

Dry Ice

短期保存温度

-80°C

長期保存温度

-80°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The GPCR GPR85 also known as Super Conserved Receptor Expressed in the Brain 2 (SREB2) is a G-protein coupled receptor. It weighs approximately 43 kilodaltons. GPR85 is mostly expressed in the central nervous system especially in areas such as the cerebral cortex and hippocampus. The structure of GPCRs including GPR85 enables these receptors to extend across the cell membrane seven times which allows them to transmit signals from extracellular space into the cell.

Biological function summary

GPR85 plays a role in modulating neuronal signal transduction. It is part of the family of GPCRs that connects external signal molecules to internal cellular responses. Though GPR85 does not form multi-protein complexes often it influences neuronal functions and developmental processes. Its signaling can affect neurotransmitter release impacting brain function and neural connectivity.

Pathways

Researchers place GPR85 in pathways related to neurodevelopment and synaptic transmission. GPR85 involves itself in the GPCR signaling pathway and neuroactive ligand-receptor interaction path. It relates to proteins like GPR84 and other GPCRs sharing signaling mechanisms that influence brain physiology. GPR85 can carry out vital functions that connect extracellular signals with intracellular activities important for neuronal health.

Scientists associate GPR85 with schizophrenia and cognitive disorders. Alterations in GPR85 expression or function may contribute to these conditions potentially disrupting normal neural signaling and connectivity. GPR85 might interact with proteins such as GPR88 which are also involved in cognitive functions suggesting a complex network of GPCRs in maintaining proper mental health. Understanding these interactions helps in developing therapeutic approaches for brain-related disorders.

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製品の性状

製品の状態

Liquid

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一般的な情報

機能

Orphan receptor.

配列の類似性

Belongs to the G-protein coupled receptor 1 family.

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Orphan receptor.

See full target information GPR85

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Abcam product promise

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Recombinant Human GPCR GPR85 protein (GST tag N-Terminus)