Recombinant Human GDF15 protein (ab125769)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human GDF15 protein
GDF15 タンパク質・ペプチド 製品一覧 -
生理活性
ab125769 is a non-glycosylated, disulfide linked homodimer. It is comprised of two identical 120 amino acid monomers. -
精製度
> 95 % SDS-PAGE. -
エンドトキシン・レベル
< 1.000 Eu/µg -
発現系
Escherichia coli -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI -
領域
197 to 308 -
配列の追加情報
This product refers to the processed mature form of this protein from aa 195 to 308. The signal peptide and propeptide are removed. MW: 12.4 kDa (monomer), 24.8 kDa (dimer).
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab125769 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Lyophilized -
備考
This product is manufactured by BioVision, an Abcam company and was previously called 4569 GDF-15, Human Recombinant. 4569-20 is the same size as the 20 µg size of ab125769.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).
Constituent: 0.1% Trifluoroacetic acid
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再構成Centrifuge vial before opening. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml.
関連情報
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別名
- GDF 15
- GDF-15
- Gdf15
see all -
組織特異性
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney. -
配列類似性
Belongs to the TGF-beta family. -
細胞内局在
Secreted. - Information by UniProt
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab125769 は 1 報の論文で使用されています。
- Olsen OE et al. TGF-ß contamination of purified recombinant GDF15. PLoS One 12:e0187349 (2017). PubMed: 29161287