AB114893

Recombinant Human GAA protein (GST tag N-Terminus)

Name: Recombinant Human GAA protein (ab114893) | Abcam
Brand: Abcam Limited
SKU: AB114893
Price: 125000 JPY
Availability: InStock

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Recombinant Human GAA protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 952 aa range, expressed in Wheat germ, with >80%, suitable for SDS-PAGE, ELISA, WB.

別名を表示する

Lysosomal alpha-glucosidase, Acid maltase, Aglucosidase alfa, GAA

1 Images

SDS-PAGE - Recombinant Human GAA protein (GST tag N-Terminus) (AB114893)

SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human GAA protein (GST tag N-Terminus) (AB114893)

12.5% SDS-PAGE showing ab114893 at approximately 130.79kDa.
Stained with Coomassie Blue.

Key facts

精製度

>80%

発現系

Wheat germ

アプリケーション

SDS-PAGE, ELISA, WB

applications

生物活性

アクセッション番号

P10253

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 8 Constituents: 0.79% Tris HCl, 0.3% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"Recombinant protein" } } }

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配列情報

[{"sequence":"MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPRVHSRAPSPLYSVEFSEEPFGVIVHRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPIEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC","proteinLength":"Full Length","predictedMolecularWeight":"130.79 kDa","actualMolecularWeight":null,"aminoAcidEnd":952,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"P10253","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

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出荷温度及び保存条件

出荷温度

Dry Ice

短期保存温度

-80°C

長期保存温度

-80°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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製品の性状

製品の状態

Liquid

補足情報

Glutathione Sepharose

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一般的な情報

機能

Essential for the degradation of glycogen in lysosomes (PubMed : 14695532, PubMed : 18429042, PubMed : 1856189, PubMed : 7717400). Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans (PubMed : 29061980).

配列の類似性

Belongs to the glycosyl hydrolase 31 family.

翻訳後修飾

The different forms of acid glucosidase are obtained by proteolytic processing.. Phosphorylation of mannose residues ensures efficient transport of the enzyme to the lysosomes via the mannose 6-phosphate receptor.

細胞内局在性

Lysosome

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information Lysosomal alpha-glucosidase

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Abcam product promise

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Recombinant Human GAA protein (GST tag N-Terminus)