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Recombinant Human FKBP12 protein (ab61244)

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SDS-PAGE - Recombinant Human FKBP12 protein (ab61244)

    Key features and details

    • Expression system: Escherichia coli
    • Purity: > 90% SDS-PAGE
    • Suitable for: SDS-PAGE

    製品の詳細

    特性

    Our Abpromise guarantee covers the use of ab61244 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      SDS-PAGE

    • 製品の状態

      Liquid

    • 備考

       

      This protein can be used for testing rapamycin inhibition of mTOR.

    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.50
      Constituents: 0.0038% EGTA, 0.00174% PMSF, 0.00385% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.79% Tris HCl, 0.00292% EDTA, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride

    関連情報

    • 別名

      • 12 kDa FK506-binding protein
      • 12 kDa FKBP
      • Calstabin 1
      • FK506 binding protein 1
      • FK506 binding protein 12
      • FK506 binding protein 1A
      • FK506 binding protein 1A (12kD)
      • FK506 binding protein 1A 12kDa
      • FK506 binding protein T cell 12 kD
      • FK506 binding protein, T cell, 12 kD
      • FK506 binding protein12
      • FK506-binding protein 1A
      • FKB1A_HUMAN
      • FKBP 12
      • FKBP 1A
      • FKBP-12
      • FKBP-1A
      • FKBP1
      • FKBP12
      • FKBP12 Exip3
      • FKBP12C
      • fkbp1a
      • Immunophilin FKBP12
      • Peptidyl prolyl cis trans isomerase
      • Peptidyl-prolyl cis-trans isomerase FKBP1A
      • PKC12
      • PKCI2
      • PPIase
      • PPIase FKBP1A
      • Protein kinase C inhibitor 2
      • Rotamase
      see all

    • 機能

      May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

    • 配列類似性

      Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
      Contains 1 PPIase FKBP-type domain.

    • 細胞内局在

      Cytoplasm.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human FKBP12 protein (ab61244)
      SDS-PAGE - Recombinant Human FKBP12 protein (ab61244)

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab61244 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab61244 は論文での使用が確認できていません。

    レビューと Q&A

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    Question


    I'm interested in some of yours product:
    - cMET cytosolic domain_recombinant protein # ab60334
    - FKBP12 recombinant protein # ab61244.
    I can't check on datasheets any info about aminoacidic sequence.

    Read More
    Answer



    Human FKBP12 (ab61244) is provided as full length protein with N-terminal His tag, MW= 13.1 kDa, expressed in E.coli expression system.

    Active Met (c-Met) protein fragment (ab60334) is a recombinant rat MET (958-end) expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

    Read More

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