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AB78877

Recombinant Human Ferritin Heavy Chain protein

Recombinant Human Ferritin Heavy Chain protein

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(2 Publications)

Recombinant Human Ferritin Heavy Chain protein is a Human Full Length protein, in the 1 to 183 aa range, expressed in Escherichia coli, with >95%, suitable for SDS-PAGE, ELISA, WB.

別名を表示する

FTH, FTHL6, OK/SW-cl.84, PIG15, FTH1, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein

2 Images
Western blot - Recombinant Human Ferritin Heavy Chain protein (AB78877)
  • WB

Unknown

Western blot - Recombinant Human Ferritin Heavy Chain protein (AB78877)

All lanes:

Western blot - Anti-Ferritin Heavy Chain antibody (<a href='/products/primary-antibodies/ferritin-heavy-chain-antibody-ab65080'>ab65080</a>) at 1 µg/mL

Lane 1:

Western blot - Recombinant Human Ferritin Heavy Chain protein (ab78877) at 0.1 µg

Lane 2:

Western blot - Recombinant Human Ferritin Heavy Chain protein (ab78877) at 0.01 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-preadsorbed-ab97080'>ab97080</a>) at 1/5000 dilution

Predicted band size: 21 kDa

true

Exposure time: 30s

SDS-PAGE - Recombinant Human Ferritin Heavy Chain protein (AB78877)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Ferritin Heavy Chain protein (AB78877)

15% SDS-PAGE showing ab78877 at approximately 21kDa (3μg).

Key facts

精製度

>95% SDS-PAGE

発現系

Escherichia coli

タグ

Tag free

アプリケーション

WB, SDS-PAGE, ELISA

applications

生物活性

No

アクセッション番号

P02794

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 7.5 Constituents: 10% Glycerol (glycerin, glycerine), 0.242% Tris, 0.0154% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p>ab78877 can be used as a WB positive control in conjunction with <a href='/products/primary-antibodies/ferritin-heavy-chain-antibody-ab65080'>ab65080</a>.</p>" } } }
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配列情報

[{"sequence":"MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDNES","proteinLength":"Full Length","predictedMolecularWeight":"21 kDa","actualMolecularWeight":null,"aminoAcidEnd":183,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"P02794","tags":[]}]
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出荷温度及び保存条件

出荷温度
Blue Ice
短期保存温度
-20°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
False
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製品の性状

製品の状態

Liquid

補足情報

ab78877is purified using conventional chromatography techniques.

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一般的な情報

機能

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed : 9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed : 9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed : 24695223, PubMed : 26436293).

配列の類似性

Belongs to the ferritin family.

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製品プロトコール

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ターゲットの情報

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed : 9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed : 9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed : 24695223, PubMed : 26436293).
See full target information FTH1
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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Cell death discovery 8:426 PubMed36284090

2022

Ferrostatin-1 alleviates tissue and cell damage in diabetic retinopathy by improving the antioxidant capacity of the Xc-GPX4 system.

Applications

Unspecified application

Species

Unspecified reactive species

Jingzhi Shao,Zhouxian Bai,Lirong Zhang,Fengyan Zhang

Annals of the rheumatic diseases 71:943-7 PubMed22228484

2012

Association of ferritin autoantibodies with giant cell arteritis/polymyalgia rheumatica.

Applications

ELISA

Species

Unspecified reactive species

N T Baerlecken,A Linnemann,W L Gross,F Moosig,T R Vazquez-Rodriguez,M A Gonzalez-Gay,J Martin,I Kötter,J C Henes,I Melchers,P Vaith,R E Schmidt,T Witte
View all publications
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組合せ製品

Primary Antibodies

AB316005

Anti-TIP49A antibody [EPR28169-31] - BSA and Azide free

BOND RX™ Validated|Recombinant|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TIP49A antibody [EPR28169-31] - BSA and Azide free (AB316005)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB75973

Anti-Ferritin heavy chain antibody [EPR3004Y]

RabMAb|Recombinant|KO Validated

Western blot - Anti-Ferritin heavy chain antibody [EPR3004Y] (AB75973)

  • 4
  • 7
Proteins & Peptides

AB158473

Recombinant Human Ferritin Light Chain protein

SDS-PAGE - Recombinant Human Ferritin Light Chain protein (AB158473)

  • 0
  • 0

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