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Recombinant Human Fas Ligand Protein (ab283899)

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SDS-PAGE - Recombinant Human Fas Ligand Protein (ab283899)

    Key features and details

    • Expression system: HEK 293 cells
    • Purity: >= 95% HPLC
    • Endotoxin level: <= 0.005 Eu/µg
    • Suitable for: SDS-PAGE

    製品の詳細

    • 製品名

      Recombinant Human Fas Ligand Protein
      Fas Ligand タンパク質・ペプチド 製品一覧

    • 精製度

      >= 95 % HPLC.
      SDS PAGE>=95% Purity

    • エンドトキシン・レベル

      <=0.005 Eu/µg

    • 発現系

      HEK 293 cells

    • アクセッション番号

      P48023

    • タンパク質長

      Full length protein

    • Animal free

      Yes

    • キャリア・フリー

      はい

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        PSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLSGVKYKKGGLVI NETGLYFVYSKVYFRGQSCNNLPLSHKVYMRNSKYPQDLVMMEGKMMSYC TTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL

      • 予測される分子量

        17 kDa

      • 実際の分子量

        17 kDa

      • 分子量情報

        Predicted MW is 16945.5 (+/- 10 Da by EDI-TOF).

      • 領域

        134 to 281

      • 配列の追加情報

        N-terminal glycine.

    特性

    Our Abpromise guarantee covers the use of ab283899 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      SDS-PAGE

    • 製品の状態

      Lyophilized
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped at Room Temperature. Store at Room Temperature.

      pH: 7.40
      Constituents: 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Monobasic dihydrogen potassium phosphate, 10.26% Trehalose

    • 再構成
      Lyophilized contents may appear as either a translucent film or a white powder. This variance does not affect the quality of the product. Store lyophilized form at room temperature. Reconstitute in phosphate buffered saline, aliquot and store at -80°C for 12 months or +4°C for 1 week. Avoid repeated freeze-thaw.

    関連情報

    • 別名

      • ALPS1B
      • Apoptosis (APO 1) antigen ligand 1
      • Apoptosis antigen ligand
      • Apoptosis antigen ligand 1
      • APT1LG1
      • APTL
      • CD178
      • CD178 antigen
      • CD95 ligand
      • CD95-L
      • CD95L
      • CD95L protein
      • Fas antigen ligand
      • Fas L
      • Fas ligand
      • Fas ligand (TNF superfamily member 6)
      • FASL
      • Fasl Fas ligand (TNF superfamily member 6)
      • FASLG
      • Generalized lymphoproliferative disease
      • Gld
      • soluble form
      • TNFL6_HUMAN
      • TNFSF6
      • Tumor necrosis factor (ligand) superfamily member 6
      • Tumor necrosis factor ligand superfamily member 6
      see all

    • 機能

      Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

    • 関連疾患

      Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly.

    • 配列類似性

      Belongs to the tumor necrosis factor family.

    • 翻訳後修飾

      N-glycosylated.
      The soluble form derives from the membrane form by proteolytic processing.

    • 細胞内局在

      Cell membrane. Secreted. May be released into the extracellular fluid, probably by cleavage form the cell surface.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human Fas Ligand Protein (ab283899)
      SDS-PAGE - Recombinant Human Fas Ligand Protein (ab283899)

      SDS-PAGE analysis of ab283899. 

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab283899 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab283899 は論文での使用が確認できていません。

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