Key features and details
- Expression system: CHO cells
- Purity: > 90% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, HPLC, SDS-PAGE
製品名Recombinant human Enterokinase protein (Active)
Enterokinase タンパク質・ペプチド 製品一覧
Sequentially cleaves carboxyl side of D-D-D-D-K.
精製度> 90 % SDS-PAGE.
>90 % by HPLC.
タンパク質長Full length protein
配列の追加情報Consists of two polypeptide chains (784 aa heavy chain and 235 aa light chain) held together by a single disulfide bond, resulting in formation of a biologically active heterodimer.
Our Abpromise guarantee covers the use of ab245805 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Human Enterokinase is expressed as a linear 1019 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of Enterokinase, which consists of two polypeptide chains (heavy chain and light chain) held together by a single disulfide bond, resulting in formation of a biologically active heterodimer. The heavy chain consists of 784 amino acid residues, and the light chain consists of 235 amino acid residues.
Concentration information loading...
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 0.16% Sodium phosphate, 0.01% Calcium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
再構成Reconstitute in water to 0.1-1.0 mg/ml.
- PRSS 7
機能Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
組織特異性Intestinal brush border.
関連疾患Defects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD) [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.
配列類似性Belongs to the peptidase S1 family.
Contains 2 CUB domains.
Contains 2 LDL-receptor class A domains.
Contains 1 MAM domain.
Contains 1 peptidase S1 domain.
Contains 1 SEA domain.
Contains 1 SRCR domain.
翻訳後修飾The chains are derived from a single precursor that is cleaved by a trypsin-like protease.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.