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Recombinant Human DIO2 protein (ab152331)

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SDS-PAGE - Recombinant Human DIO2 protein (ab152331)

    Key features and details

    • Expression system: Wheat germ
    • Suitable for: WB, SDS-PAGE, ELISA

    製品の詳細

    • 製品名

      Recombinant Human DIO2 protein

    • 発現系

      Wheat germ

    • アクセッション番号

      Q92813

    • タンパク質長

      Protein fragment

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        PSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRM DNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSKR

      • 予測される分子量

        37 kDa including tags

      • 領域

        166 to 265

    特性

    Our Abpromise guarantee covers the use of ab152331 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      Western blot

      SDS-PAGE

      ELISA

    • 製品の状態

      Liquid
    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

      pH: 8.00
      Constituents: 0.31% Glutathione, 0.79% Tris HCl

    関連情報

    • 別名

      • 5DII
      • D2
      • Deiodinase, iodothyronine, type II
      • DIO2
      • DIOII
      • EC 1.97.1.10
      • IOD2_HUMAN
      • ITDI2
      • SelY
      • Thyroxine deiodinase, type II
      • TXDI2
      • Type 2 DI
      • Type 2 iodothyronine deiodinase
      • Type II 5' deiodinase
      • Type II iodothyronine deiodinase
      • Type-II 5''-deiodinase
      see all

    • 機能

      Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.

    • 組織特異性

      Heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain.

    • 配列類似性

      Belongs to the iodothyronine deiodinase family.

    • 翻訳後修飾

      Ubiquitinated by MARCH6, leading to its degradation by the proteasome. Deubiquitinated by USP20 and USP33.

    • 細胞内局在

      Membrane.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human DIO2 protein (ab152331)
      SDS-PAGE - Recombinant Human DIO2 protein (ab152331)
      12.5% SDS-PAGE analysis of ab152331 stained with Coomassie Blue.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab152331 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab152331 は論文での使用が確認できていません。

    レビューと Q&A

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