Recombinant Human Cytokeratin 5 protein (GST tag N-Terminus)
Recombinant Human Cytokeratin 5 protein (GST tag N-Terminus)
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Recombinant Human Cytokeratin 5 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 590 aa range, expressed in Wheat germ, with >80%, suitable for SDS-PAGE, ELISA, WB.
別名を表示する
58 kDa cytokeratin, Cytokeratin-5, Keratin-5, Type-II keratin Kb5, CK-5, K5, KRT5, CK5
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human Cytokeratin 5 protein (GST tag N-Terminus) (AB132931)
12.5% SDS-PAGE analysis of ab132931 stained with Coomassie Blue
Reactivity data
配列情報
出荷温度及び保存条件
製品の状態
精製方法
出荷温度
短期保存温度
長期保存温度
分注に関する情報
保管に関する情報
一般的な情報
機能
Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity).
配列の類似性
Belongs to the intermediate filament family.
翻訳後修飾
Phosphorylated by CDK1, AURKB and Rho-kinase, phosphorylation is regulated by the cell cycle (By similarity). Thr-24 phosphorylation, mediated by CDK1, peaks during prometaphase or metaphase cells with phosphorylated filamentous structures evident throughout the cytoplasm during early mitosis (By similarity). CDK1 phosphorylates Thr-24 in mitotic cells at the site of injury (By similarity).. O-glycosylated.
ターゲットの情報
Abcam product promise
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