Recombinant Human Constitutive androstane receptor protein (ab83193)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% Affinity purified
- Suitable for: Functional Studies
製品の詳細
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製品名
Recombinant Human Constitutive androstane receptor protein -
生理活性
1 unit equals 1 nanogram of purified protein. -
精製度
> 90 % Affinity purified.
Recombinant ab83193 was expressed in a E.coli system and purified by an affinity column in combination with FPLC chromatography. The purified recombinant protein is greater than 90% homogeneous and contains no detectable protease, DNase and RNase activity. -
発現系
Escherichia coli -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human
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特性
Our Abpromise guarantee covers the use of ab83193 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Functional Studies
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製品の状態
Liquid -
備考
1 unit equals 1 nanogram of purified protein. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.9
Constituents: 0.75% Potassium chloride, 0.0154% DTT, 0.316% Tris HCl, 0.00584% EDTA, 20% Glycerol (glycerin, glycerine)
関連情報
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別名
- CAR
- CAR BETA
- CAR1
see all -
機能
Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. -
組織特異性
Predominantly expressed in liver. -
配列類似性
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
ドメイン
Composed by a short N-terminal domain followed by the DNA binding, hinge, and ligand binding/dimerization domains. -
翻訳後修飾
Phosphorylated at Thr-38 by PKC, dephosphorylation of Thr-38 is required for nuclear translocation and activation. -
細胞内局在
Nucleus. Cytoplasm. Cytoplasm > cytoskeleton. Recruited to the cytoplasm by DNAJC7. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab83193 は論文での使用が確認できていません。