Recombinant Human CLLD8/SETDB2 protein (ab169554)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 80% Densitometry
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Human CLLD8/SETDB2 protein -
精製度
> 80 % Densitometry.
Affinity purified. -
発現系
Baculovirus infected Sf9 cells -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MGEKNGDAKTFWMELEDDGKVDFIFEQVQNVLQSLKQKIKDGSATNKEYI QAMILVNEATIINSSTSIKDPMPVTQKEQENKSNAFPSTSCENSFPEDCT FLTTGNKEILSLEDKVVDFREKDSSSNLSYQSHDCSGACLMKMPLNLKGE NPLQLPIKCHFQRRHAKTNSHSSALHVSYKTPCGRSLRNVEEVFRYLLET ECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEID SRKLPQFKYRKTVWPRAYNLTNFSSMFTDSCDCSEGCIDITKCACLQLTA RNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQ HGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLSRANTEKSYGI DENGRDENTMKNIFSKKRKLEVACSDCEVEVLPLGLETHPRTAKTEKCPP KFSNNPKELTMETKYDNISRIQYHSVIRDPESKTAIFQHNGKKMEFVSSE SVTPEDNDGFKPPREHLNSKTKGAQKDSSSNHVDEFEDNLLIESDVIDIT KYREETPPRSRCNQATTLDNQNIKKAIEVQIQKPQEGRSTACQRQQVFCD EELLSETKNTSSDSLTKFNKGNVFLLDATKEGNVGRFLNHSCCPNLLVQN VFVETHNRNFPLVAFFTNRYVKARTELTWDYGYEAGTVPEKEIFCQCGVN KCRKKIL -
予測される分子量
120 kDa including tags -
領域
1 to 719 -
タグ
GST tag N-Terminus
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab169554 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
関連情報
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別名
- C13orf4
- Chromosome 13 open reading frame 4
- Chronic lymphocytic leukemia deletion region 8
see all -
機能
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis. -
組織特異性
Ubiquitous. Highest expression in heart, testis and ovary. -
配列類似性
Belongs to the histone-lysine methyltransferase family.
Contains 1 MBD (methyl-CpG-binding) domain.
Contains 1 pre-SET domain.
Contains 1 SET domain. -
細胞内局在
Nucleus. Chromosome. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human CLLD8/SETDB2 protein (ab169554)SDS-PAGE analysis of ab169554.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab169554 は 1 報の論文で使用されています。
- Li H et al. MiR-122 Promotes the Development of Colon Cancer by Targeting ALDOA In Vitro. Technol Cancer Res Treat 18:1533033819871300 (2019). PubMed: 31564215