AB164948

Recombinant Human CGB5 protein (GST tag N-Terminus)

Name: Recombinant Human CGB5 protein (ab164948) | Abcam
Brand: Abcam Limited
SKU: AB164948
Price: 118000 JPY
Availability: InStock

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Recombinant Human CGB5 protein (GST tag N-Terminus) is a Human Full Length protein, in the 1 to 165 aa range, expressed in Wheat germ, suitable for ELISA, WB.

別名を表示する

CGB, CGB5, CGB8, CGB3, Choriogonadotropin subunit beta 3, Choriogonadotropin subunit beta, Chorionic gonadotropin chain beta, CG-beta

1 Images

SDS-PAGE - Recombinant Human CGB5 protein (GST tag N-Terminus) (AB164948)

SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human CGB5 protein (GST tag N-Terminus) (AB164948)

ab164948 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

発現系

Wheat germ

アプリケーション

ELISA, WB

applications

生物活性

アクセッション番号

P0DN86

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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配列情報

[{"sequence":"MEMFQGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVLPALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDCGGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ","proteinLength":"Full Length","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":165,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"P0DN87","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

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出荷温度及び保存条件

出荷温度

Dry Ice

短期保存温度

-80°C

長期保存温度

-80°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CGB5 also known as chorionic gonadotropin subunit beta 5 is a protein closely related to the hormonal function in mammals. It belongs to the beta subunit of the human chorionic gonadotropin (hCG) hormone. This protein has a molecular mass of approximately 22 kDa and is expressed mainly in the placenta. Its expression is highly regulated during pregnancy contributing to various reproductive processes.

Biological function summary

The chorionic gonadotropin subunit beta 5 plays a significant role in supporting the uterine environment. It is a critical part of the larger glycoprotein hormone complex which includes the alpha subunit. This complex interacts with luteinizing hormone/chorionic gonadotropin receptors (LHCGR) in the ovary facilitating the maintenance of the corpus luteum and promoting progesterone production. This biological activity is important for successful embryonic implantation and maintenance of early pregnancy.

Pathways

CGB5 is integral to the reproductive and hormonal regulatory pathways. It actively participates in the gonadotropin-releasing hormone pathway which influences other key hormones involved in reproductive functions. Within this pathway CGB5 interacts with luteinizing hormone (LH) as both play critical roles in fertility and menstrual regulation processes.

CGB5 shows associations with trophoblastic diseases such as choriocarcinoma and other gestational trophoblastic diseases. Abnormal expression or mutations in CGB5 can result in gestational trophoblastic neoplasms. Its disease association is often understood alongside other proteins like CGB7 which share similar functions in the beta subunit family. Understanding these connections helps in targeted interventions and therapeutic strategies to manage related reproductive health issues.

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製品の性状

製品の状態

Liquid

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一般的な情報

機能

Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role in pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

配列の類似性

Belongs to the glycoprotein hormones subunit beta family.

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information CGB3

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Abcam product promise

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Recombinant Human CGB5 protein (GST tag N-Terminus)