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Recombinant Human CDNF protein (ab185829)

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Key features and details

  • Expression system: Mammalian
  • Purity: > 95% SDS-PAGE
  • Endotoxin level: < 1.000 Eu/µg
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

製品の詳細

  • 製品名

    Recombinant Human CDNF protein
    CDNF タンパク質・ペプチド 製品一覧

  • 精製度

    > 95 % SDS-PAGE.
    Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.

  • エンドトキシン・レベル

    < 1.000 Eu/µg

  • 発現系

    Mammalian

  • アクセッション番号

    Q49AH0

  • タンパク質長

    Full length protein

  • Animal free

    No

  • 由来

    Recombinant

    • 生物種

      Human

    • 配列

      QGQEAGGRPGADCEVCKEFLNRFYKSLIDRGVNFSLDTIEKELISFCLDT KGKENRLCYYLGATKDAATKILSEVTRPMSVHMPAMKICEKLKKLDSQIC ELKYEKTLDLASVDLRKMRVAELKQILHSWGEECRACAEKTDYVNLIQEL APKYAATHPKTELHHHHHH

    • 予測される分子量

      19 kDa including tags

    • 領域

      25 to 187

    • タグ

      His tag C-Terminus

特性

Our Abpromise guarantee covers the use of ab185829 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    HPLC

  • 製品の状態

    Lyophilized
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.88% Sodium chloride, 99% Phosphate Buffer

  • 再構成
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 3X PBS. After reconstitution aliquot and store at < -20°C, avoid freeze/thaw cycles.

関連情報

  • 別名

    • Arginine rich mutated in early stage tumors like 1
    • ARMET L1
    • ARMET like protein 1
    • ARMET-like protein 1
    • ARMETL 1
    • ARMETL1
    • CDNF
    • CDNF_HUMAN
    • Cerebral dopamine neurotrophic factor
    • Conserved dopamine neurotrophic factor
    see all

  • 機能

    Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.

  • 組織特異性

    Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.

  • 配列類似性

    Belongs to the ARMET family.

  • 細胞内局在

    Secreted.
  • Information by UniProt

プロトコール

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

参考文献 (0)

ab185829 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab185829 は論文での使用が確認できていません。

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