Recombinant Human CDK13 protein (GST tag N-Terminus)
Recombinant Human CDK13 protein (GST tag N-Terminus)
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Recombinant Human CDK13 protein (GST tag N-Terminus) is a Human Fragment protein, in the 1 to 90 aa range, expressed in Wheat germ, suitable for ELISA, WB.
別名を表示する
CDC2L, CDC2L5, CHED, KIAA1791, CDK13, Cyclin-dependent kinase 13, CDC2-related protein kinase 5, Cell division cycle 2-like protein kinase 5, Cell division protein kinase 13, Cholinesterase-related cell division controller, hCDK13
- SDS-PAGE
Unknown
SDS-PAGE - Recombinant Human CDK13 protein (GST tag N-Terminus) (AB160115)
ab160115 on a 12.5% SDS-PAGE stained with Coomassie Blue.
Reactivity data
製品の詳細
配列情報
出荷温度及び保存条件
出荷温度
長期保存温度
分注に関する情報
保管に関する情報
製品の性状
製品の状態
Liquid
一般的な情報
機能
Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
配列の類似性
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
細胞内局在性
Nucleus speckle
ターゲットの情報
Abcam product promise
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