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Recombinant Human CD74 protein (His tag) (ab174039)

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SDS-PAGE - Recombinant Human CD74 protein (His tag) (ab174039)

    Key features and details

    • Expression system: HEK 293 cells
    • Purity: > 95% SDS-PAGE
    • Endotoxin level: < 1.000 Eu/µg
    • Tags: His tag N-Terminus
    • Suitable for: SDS-PAGE

    製品の詳細

    • 製品名

      Recombinant Human CD74 protein (His tag)
      CD74 タンパク質・ペプチド 製品一覧

    • 精製度

      > 95 % SDS-PAGE.

    • エンドトキシン・レベル

      < 1.000 Eu/µg

    • 発現系

      HEK 293 cells

    • アクセッション番号

      P04233-2

    • タンパク質長

      Protein fragment

    • Animal free

      No

    • 由来

      Recombinant

      • 生物種

        Human

      • 配列

        QQQGRLDKLTVTSQNLQLENLRMKLPKPPKPVSKMRMATPLLMQALPMGA LPQGPMQNATKYGNMTEDHVMHLLQNADPLKVYPPLKGSFPENLRHLKNT METIDWKVFESWMHHWLLFEMSRHSLEQKPTDAPPKESLELEDPSSGLGV TKQDLGPVPM

      • 予測される分子量

        19 kDa including tags

      • 領域

        73 to 232

      • タグ

        His tag N-Terminus

      • 配列の追加情報

        Human CD74, His Tag (CD4-H524c) is expressed from human 293 cells (HEK293). It contains AA Gln 73 - Met 232 (Accession # NP_004346.1).

    特性

    Our Abpromise guarantee covers the use of ab174039 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • アプリケーション

      SDS-PAGE

    • 製品の状態

      Lyophilized

    • 備考

      Lyophilized from 0.22 μm filtered solution.

    • Concentration information loading...

    前処理および保存

    • 保存方法および安定性

      Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 95% PBS, 5% Trehalose

    • 再構成
      Reconstitute with sterile deionized water to a concentration of 400 µg/ml.

    関連情報

    • 別名

      • CD 74
      • CD74
      • CD74 antigen
      • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
      • CD74 molecule
      • CD74 molecule, major histocompatibility complex, class II invariant chain
      • CLIP
      • DHLAG
      • Gamma chain of class II antigens
      • HG2A_HUMAN
      • HLA class II histocompatibility antigen gamma chain
      • HLA DR antigens associated invariant chain
      • HLA DR gamma
      • HLA-DR antigens-associated invariant chain
      • HLA-DR-gamma
      • HLADG
      • HLADR antigens associated invariant chain
      • Ia antigen associated invariant chain
      • Ia antigen-associated invariant chain
      • Ia associated invariant chain
      • Ia gamma
      • Ii
      • Invariant polypeptide of major histocompatibility complex class II antigen associated
      • la-gamma
      • Major histocompatibility complex class II invariant chain
      • MHC HLA DR gamma chain
      • MHC HLA-DR gamma chain
      • p33
      • p35
      • Protein 41
      see all

    • 機能

      Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

    • 配列類似性

      Contains 1 thyroglobulin type-1 domain.

    • 細胞内局在

      Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus > trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.
    • Information by UniProt

    画像

    • SDS-PAGE - Recombinant Human CD74 protein (His tag) (ab174039)
      SDS-PAGE - Recombinant Human CD74 protein (His tag) (ab174039)
      SDS-PAGE analysis of ab174039 under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab174039 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab174039 は論文での使用が確認できていません。

    レビューと Q&A

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